Mobay Corporation

Other

Bayer Corporation

Richard E Parizek

Sharon A Bryant

Karen K Brown

Richard C Stewart

Louis J Travalent

Lonny E Vlieger

Michael J McGinley

Stuart K Nibbelink

Larry F Moore

Disclosed herein is a multicomponent low dose vaccine comprising a safe and immunogenically effective combination of a protective antigen component or components of clostridial organism, a protective antigen component of a non-clostridial organism and an adjuvant.

Multicomponent vaccine containing clostridial and non-clostridial organisms in a low dose

A vaccine effective against S. zooepidemicus-caused infections is made by enzymatic digestion of S. zooepidemicus and subsequent detergent treatment of the product of this digestion. The antigenic material thus obtained is then combined with an appropriate adjuvant.

Preparation and use of enzyme-detergent extracted Streptococcus

A device for administering antigenic material to a horse intranasally. This device is composed of a hollow tube and a blocking device. The hollow tube is long enough to reach the tonsilor tissue of a horse. This tube has a sealed end and a tapered open end. At least one opening, preferably openings along the length of this tube are positioned in a manner such that antigenic material which exits through them will reach the tonsilor tissue of the horse. The blocking device sits on the hollow tube at the point where the tapering of the open end begins. A syringe containing antigenic material is positioned at the tapered open end of the hollow tube and the antigenic material is then released in the form of small droplets on the tonsilor tissue of the horse.

Applicator for intranasal administration of vaccines to horses

A process is provided for increasing the yield of active cells of Treponema hyodysenteriae by growing such cells in a nutrient medium containing a cholesterol-rich bovine fraction. Killed cells grown in this manner can be used to produce a bacterin which is effective against swine dysentery.

Process for growth of treponema hyodysenteriae

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Lenexa, KS, United States of America

Richard E Parizek