King's College London

Imperial College Innovations Limited

Ucl Business Plc

Richard Cook

Timothy Watson

Frederic Festy

Larry L Hench

Garrit Koller

Ian D Thompson

Sebastien Ourselin

Baptiste Allain

David Hawkes

Federico Foschi

Laurence Lovat

Francesco Mannocci

Paul D Robinson

Mingxing Hu

An endoscopic apparatus and method to capture an image of in-vivo tissue with automatic exposure control. For example, the method includes capturing image data on an image sensor and analyzing an indication of brightness of each pixel to determine whether the captured image data is saturated. When the image data is saturated, the method includes reducing the exposure period by a first increment, and repeating the capturing and analyzing steps until the captured image data is not saturated. When the captured image data is not saturated, in some embodiments, the method includes analyzing the indication of brightness of each pixel compared to a threshold indicative of use of a proportion of an available dynamic range of the image sensor, and when it is determined that the threshold has not been reached, increasing the exposure period by a second increment that has a magnitude relative to the first increment.

Automatic exposure control for endoscopic imaging

A method and apparatus for detecting the presence of the viable cells in an endodontic sample in or taken from an endodontic cavity in the tooth, such as the root canal, enables the rapid and low cost identification of the presence or absence of bacteria or other viable cell tissue in the endodontic space by first incubating a viable cell indicator with an endodontic sample for a pre-determined period suitable for chair-side test and then measuring and/or detecting a change in a parameter (e.g. fluorescence) associated with the viable cell indicator. Thereby, the required level of root canal treatment can be reached which minimizes the risk of re-infection without the time, cost and potentially harm of over-preparation and over treatment by the dental surgeon or of a re-treatment.

Method for detecting the presence of the viable cells in an endodontic sample

An apparatus and a computer-implemented method are provided for determining a location in a target image (T) of a site on a surface of a physical object using two or more reference images (I, I) of said physical object that have been obtained with a reference imaging device. Each of said two or more reference images includes said site on the surface of the physical object and was obtained with the reference imaging device having a different position and/or orientation relative to said physical object. The target image is obtained by a target imaging device and includes the site on the surface of the physical object. For each reference image, a set of feature mappings from the reference image to the target image is used to determine the epipolar geometry between the reference image and the target image, and a projection of the site from the reference image onto the target image is calculated from said epipolar geometry. The location in the target image of the site on the surface of the physical object is determined from the calculated epipolar projections for the two or more reference images.

Apparatus and method for determining a location in a target image

Mouthpiece

The invention relates to an apparatus and a method for imaging the vascular structure and vascular blood flow of an organ or tissue and, in particular, relates to a selective wavelength epi-illumination endoscopic imaging apparatus to image vascular tissues and real time capillary blood flow in vivo. The invention also relates to determining the blood oxygen content of the organ or tissue.

Imaging apparatus and method

Bioactive glasses may be used as air abrasive agents in methods for treating or preventing dental hard tissue and pulpal disorders, such as dental pain.

Use of bioactive glass

The present invention relates to a method of cutting a bioactive glass object which comprises contacting the bioactive glass object with bioactive glass particles delivered using an air abrasion system.

Use of bioactive glass for cutting bioactive glasses

Growing community of inventors

London, United Kingdom

Richard Cook