American Cyanamid Company

Glaxo Group Limited

Richard Bell

Michael V Ramsay

David Noble

Derek R Sutherland

Edward P Tiley

Michael W Foxton

Brian Edgar Looker

Richard A Fletton

Hazel M Noble

John B Ward

Neil Porter

Peter D Howes

Gordon C Lawrence

Michael J Dawson

Paul D Hallam

Compounds of formula (1) ##STR1## wherein R represents a sugar residue or an acylated derivative thereof;

Macrolide compounds

Compounds of formula (1) ##STR1## wherein R.sup.1 represents a methyl, ethyl or isopropyl group; Y.sup.1 is --CH.sub.2 --, Y.sup.2 is --CH-- and X represents ##STR2## [where R.sup.2 represents a hydrogen atom or a group OR.sup.6 (where OR.sup.6 is a hydroxy group or a substituted hydroxyl group having up to 25 carbon atoms) and R.sup.3 represents a hydrogen atom, or R.sup.2 and R.sup.3 together with the carbon atom to which they are attached represent &gt;C.dbd.O, &gt;C.dbd.CH.sub.2 or &gt;C.dbd.NOR.sup.7 (where R.sup.7 represents a hydrogen atom, a C.sub.1-8 alkyl group or a C.sub.3-8 alkenyl group and the group &gt;C.dbd.NOR.sup.7 is in the E configuration)] or --Y.sup.1 --X--Y.sup.2 represents --CH.dbd.CH--CH-- or --CH.sub.2 --CH.dbd.C--; R.sup.4 represents a group OR.sup.6 as defined above and R.sup.5 represents a hydrogen atom, or R.sup.4 and R.sup.5 together with the carbon atom to which they are attached represent &gt;C.dbd.O or &gt;C.dbd.NOR.sup.7a ( where R.sup.7a is as defined above for R.sup.7); and one of R.sup.8 and R.sup.9 represents an alkoxyalkoxy group optionally interrupted by an oxygen atom or an alkoxy group and the other represents a hydrogen atom or R.sup.8 and R.sup.9 together with the carbon atom to which they are attached represent &gt;C.dbd.NOR.sup.7b (where R.sup.7b is as defined above for R.sup.7), and salts thereof. These compounds may be used to control nematode, acarine, insect or other pests.

Compounds of formula (I) ##STR1## and salts thereof, wherein R is a C.sub.1-4 alkyl group, R.sup.1 is a methyl, ethyl or isopropyl group; and OR.sup.2 is a hydroxyl or substituted hydroxyl group having up to 25 carbon atoms. These compounds may be used for controlling insect, acarine, nematode or other pests.

Compounds of general formula (I) ##STR1## (where R.sup.1 is a carboxyl group, a group COO.sup..crclbar. or a blocked carboxyl group;

Cephalosporin antibiotics

Compounds of general formula I ##STR1## (wherein R represents NH.sub.2 -- or an acylated or silylated amino group;

3-(Optionally substituted-but-1-en-3-ynyl) cephalosporins

Growing community of inventors

South Ruislip, United Kingdom

Richard Bell