Cook Medical Technologies LLC

Cook Incorporated

Med Institute Incorporated

Oregon Health & Science University

Muffin Incorporated

William Cook Europe Aps

Medical Engineering and Development Institute, Inc.

Richard B. Sisken

Fred T. Parker

Richard B Sisken

Neal E Fearnot

Brian C Case

Thomas A Osborne

Darin Gene Schaeffer

Jacob A Flagle

Andrew K Hoffa

Dusan Pavcnik

Michael L Garrison

Ram H Paul, Jr

William John Havel

Tyler Evans McLawhorn

Steven Charlebois

Vihar C Surti

Jarin A Kratzberg

Raymond B Leonard, Ii

Charles W Agnew

James D Purdy

Charles Leland Baxter

Brian D Choules

Benjamin Nickless

John Crowder Sigmon, Jr

Richard W Ducharme

Fred T Parker, Jr

Shaun D Gittard

Frank J Fischer, Jr

Michelle D Martinez

Peter S McKinnis

Gregory A Frankland

Scott K Philhower

Kenneth Aaron Haselby

Fred T Parker

Charles F Babbs

Marc C Buhrmester

Ryan Pruchnic

James Thomas Jones

Bryan Woodard

Jillian Haac

David R Wagner

Melvin Kem Hawkins

Jillian Faye Hrnicek

Kyle D Amick

Justin Metcalf

Mike Garrison

Peter S Mckinnis

William D Armstrong

Steven J Charlebois

Raymond B Ii Leonard

Dusan Pavnik

Brian L Case

A filling and sealing system is provided for efficiently filling a series of individual vials with therapeutic liquids. In particular embodiments, the system includes a filling zone or station, a sealing zone or station, an unloading zone or station, and electronic controls.

Systems and methods for filling and sealing vials

Methods and apparatus are provided for treating tissue with apparatus that includes an priming portion for initiating a healing response in the tissue to be treated, and which delivers a bioactive agent during or after preparing tissue adjacent the apparatus, as by generating or aiding a healing, regeneration or repair response in the tissue. The priming portion may comprise an abrasive surface, fluid ejection ports, and/or stimulation by electrical, thermal, or light energy.

Cell injection needle

Described in one aspect is a multi-cell or multi-chambered container for sealing various materials such as therapeutic or diagnostic agents, animal or human tissue, tissue samples, specimens, blood, genetic material, or any other material. The container includes seals formed by folding the wall of the elongate body transverse to the interior of the elongate body and maintaining the folded wall portions adjacent one another or joining them together. In another aspect, the container disclosed may be made according to a method involving creating multiple seals at various locations along the elongate body thus creating sealed voids or cells between the seals within the elongate body.

Multi-cell sealed container

A bipolar sphincterotome may include an elongate tubular member, a cutting wire, and a return path. The return path may include a conductive ink portion disposed on an outer surface at a distal portion of the tubular member. The return path may also include a return wire disposed within the tubular member that is electrically coupled to the conductive ink portion. In some example embodiments, the return wire may be disposed within a lumen configured to have two or more functions, one of which being to house the return wire. Additionally, in some example embodiments, the conductive ink portion may be circumferentially disposed on the outer surface to provide visual access to a wire guide lumen. Also, for some example embodiments, the bipolar sphincterotome may include two electrically isolated return paths.

Bipolar sphincterotome

A control unit controls delivery of RF energy generated by an RF generator to a medical device configured to perform a medical procedure. The control unit may be separate from the RF generator, and may have an input that may be attached to an output of the RF generator. The control unit includes switching circuitry that is closed while an amount of RF energy is transmitted through the control unit to the medical device. The switching circuitry opens when the amount of RF energy reaches a threshold level.

RF energy controller and method for electrosurgical medical devices

A valve prosthesis, such as an artificial venous valve, is described. The valve prosthesis has a support frame formed from a cannula and an attached covering that defines an opening adapted to move between a first position in which the opening is open to fluid flow and a second position in which the opening is closed to fluid flow. The support frame includes a leaflet support portion and a circumferential centering support element disposed adjacent the leaflet support portion with respect to a lengthwise axis of the support frame and mirroring the leaflet support portion with respect to a transverse axis of the support frame.

Implantable vascular device

A delivery system is provided with a balloon catheter having a stent mounted thereon. A retention wire is provided to restrain the stent on the balloon of the balloon catheter. The retention wire is coupled to the catheter adjacent the distal end of the stent and adjacent the proximal end of the stent. The retention wire extends along the length of the stent adjacent the outer surface thereof. Thus, the retention wire may restrain the stent from moving longitudinally during inflation of the balloon.

Stent delivery system with a retention wire

A valve prosthesis, such as an artificial venous valve, having a support frame and leaf structure comprising one or more leaflets in which the outer edge of each leaflet engages the inner circumference of the bodily passageway along a serpentine path urged against the passageway by an expandable frame, while the inner edges move in response to fluid to restrict retrograde flow. Optionally, one or more elements can extend from the support frame/leaf structure to provide centering support and/or protection from the leaflet adhering to the vessel wall. In one embodiment, the centering support structure comprises a second or third expandable frames attached to and extending from the proximal and/or distal ends of main valve structure and support frame. In another embodiment, one or more support elements extend outward from the valve support frame to engage the vessel wall to provide greater longitudinal stability.

A medical device is provided. The device includes a cannula with a lumen and a plurality of apertures and a visually perceptible indicator that is configured to allow the cannula to be positioned at an appropriate rotational position within the patient. A plurality of injection needles are disposed within the lumen and a first handle is fixed with respect to the cannula and a second handle is disposed in conjunction with the first handle and fixed to the proximal portion of each of the plurality of needles, the first handle is translatable with respect to the second handle to translate the plurality of needles from a first position where the distal portions of each of the plurality of needles are disposed within the lumen of the cannula, and a second position where the distal portion of each of the plurality of needles extends out of the lumen through their respective aperture.

Fluid injection device

Disclosed is an anchoring element for an implantable prosthesis that includes a barb, wherein the anchoring element, which includes a basal portion, comprises a thin layer of material, such as a cannula or sheet of metal, that extends or wraps at least partially around the strut of the prosthesis to which it is attached. The barb is configured to extend outward from the basal portion to penetrate adjacent tissue. The anchoring element is either permanently affixed to the strut, such as by laser or spot welding, crimping, or some other method of bonding, or allowed to slide longitudinally over the strut between two points or stops in order to relieve any excessive loads placed upon the barb that could cause fracture. The anchoring element and strut may be configured to limit axial rotation of the barb, while still allowing longitudinal movement. In another embodiment, the slidable anchoring element may be manipulated following initial deployment to reorient the barb toward the implantation site.

Anchoring barb for attachment to a medical prosthesis

An introducer apparatus and a method for forming an introducer apparatus. The apparatus comprises an inner liner having a passageway extending longitudinally therethrough. A coil in a stressed, radially expanded condition is positioned longitudinally around said inner tube. A polymeric outer tube is positioned longitudinally around the coil and the inner liner, and is bonded to the inner liner through the spaces between the turns of the coil. The polymeric outer tube is formed in a manner such that it maintains the coil in its stressed radially expanded condition. In a preferred embodiment, the inner liner and outer tube comprise a polyimide.

Flexible introducer sheath

An valve prosthesis, such as an artificial venous valve, having a support frame and leaf structure comprising one or more leaflets in which the outer edge of each leaflet engages the inner circumference of the bodily passageway along a serpentine path urged against the passageway by an expandable frame, while the inner edges move in response to fluid to restrict retrograde flow. Optionally, one or more elements can extend from the support frame/leaf structure to provide centering support and/or protection from the leaflet adhering to the vessel wall. In one embodiment, the centering support structure comprises a second or third expandable frames attached to and extending from the proximal and/or distal ends of main valve structure and support frame. In another embodiment, one or more support elements extend outward from the valve support frame to engage the vessel wall to provide greater longitudinal stability.

A medical prosthesis for implantation within the body of a patient comprises a support structure and an anchoring element that comprises a basal portion and at least one barb extending from the basal portion. The anchoring element may be slidably attached to the strut and the strut may include a first stop and a second stop that define a longitudinal zone of movement for the anchoring element. Other devices and methods are described.

Growing community of inventors

West Lafayette, IN, United States of America

Richard B Sisken