Ionian Technologies, Inc.

Queens Group, Inc.

Q2 Marketing, LLC

Titanium Metals Corporation

Abbott Diagnostics Scarborough, Inc.

Richard B Roth

William L Plumb

Jarrod Provins

Jeffrey G Mandell

Paul D Miller

Andrew P Miller

Rebecca C Holmberg

Brian K Maples

Honghua Zhang

Daiwei Shen

David G May

Karthikeyan Kumaravadivelu

Austin Matthew Derfus

Neil Quitoviera

Torsten Gliewe

Aric Joneja

Timothy L Higby

Adrian P Crute

Andrew Purse

Alan Blackburn

David May

Aspects of the present disclosure include sample preparation cartridges including a cylindrical structure and one or more covers. The cylindrical structure further includes a top, a bottom, an annular wall, a plurality of cavities in the annular wall that form a plurality of open-sided chambers on the annular wall and one or more interconnections providing fluidic communication between the plurality of chambers. The one or more covers cover the open side of the plurality of chambers. Also provided is a cylinder housing comprising one or more magnets. The sample preparation cartridge is removably disposed into the cylinder housing or adjacent to the cylinder housing. Methods of using the sample preparation device are also provided.

Sample preparation device and methods for using same

This invention relates to methods and compositions for detecting the presence or absence of a Respiratory Syncytial Virus target nucleic acid in a biological sample using isothermal nucleic acid amplification.

Nicking and extension amplification reaction (NEAR) of respiratory syncytial virus species

This invention relates to compositions, methods and kits for detecting the presence or absence of a bacterial species in a biological sample using isothermal nucleic acid amplification.

Nicking and extension amplification reaction (near) ofspecies

A method includes combining a polynucleotide and an amplification reagent mixture to form a reaction mixture, wherein the reaction mixture comprises reversibly bound divalent ions in solution, and adjusting the pH of the reaction mixture to release the reversibly bound divalent ions, thereby initiating amplification of the polynucleotide.

Nucleic acid amplifications

The invention is in general directed to the rapid exponential amplification of short DNA or RNA sequences at a constant temperature.

Nicking and extension amplification reaction for the exponential amplification of nucleic acids

[object Object]

Methods and associated apparatus for semi-continuous casting of hollow ingots are described. In one embodiment a method for the semi-continuous casting of a metallic hollow ingot is provided. The method includes providing a mold that includes a mold center having an inner pipe and an outer pipe arranged to form an annular space for a cooling media and an outer mold, circulating a cooling media in the annular space, feeding a source material to the mold, heating the source material to produce a molten material, moving the mold center progressively downward relative to the outer mold, and solidifying the molten material to form a hollow ingot. Embodiments relating to an apparatus for semi-continuous casting of hollow ingots, and products resulting from the semi-continuous casting of hollow ingots are also described.

Method and apparatus for semi-continuous casting of hollow ingots and products resulting therefrom

A media disk storage container formed of a lid pivotally connected to a base, the base being provided with a spine having a customized cover for identifying the media contents of the container, the artist, the recording company, the manufacturer of the container or other information. The spine cover preferably snaps into place over the spine.

Media disk storage container with spine cover

Video disk storage package

Digital video disk storage package

Media disk storage package

Growing community of inventors

San Diego, CA, United States of America

Richard B Roth