Cellomics, Inc.

Other

Richard A Rubin

Paul J Sammak

R Terry Dunlay

Kenneth A Giuliano

Albert H Gough

Gustavo Rosania

Bruce Ray Conway

Oleg Lapets

Randall Shopoff

Michel Nederlof

Murugan Kannan

Thomas D Duensing

The present invention provides automated methods and associated software for determining the organization of a component of interest in individual cells by determining the amount or distribution of the cellular component of interest as a function of position relative to a reference component in the individual cells.

Methods for determining the organization of a cellular component of interest

The present invention provides systems, methods, and screens to measure receptor internalization in a single step with appropriate automation and throughput. This approach involves luminescent labeling of the receptor of interest and the automated measurement of receptor internalization to a perinuclear location.

System for cell-based screening

The present invention provides methods and software for tracking individual cells during a kinetic cell screening assay.

Automated assay for identification of individual cells during kinetic assays

The present invention provides automated systems, methods, screens, and software for the analysis of cell spreading. The invention involves providing cells containing fluorescent reporter molecules in an array of locations, contacting the cells with a test stimulus, acquiring images from the cells, and automatically calculating one or more morphological features that provide a measure of cell spreading.

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Pittsburgh, PA, United States of America

Richard A Rubin