Applied Biosystems, LLC

Life Technologies Corporation

Applera Corporation

Ambion, Inc.

Richard A Jarvis

Mike Byrom

Dmitriy Ovcharenko

David Allen Brown

Brittan L Pasloske

Lance Ford

Vince Pallotta

Dmitriy Oveharenko

A system and method are described for electroporating a sample that utilizes one or more sets of electrodes that are spaced apart in order to hold a surface tension constrained sample between the electrodes. The first electrode is connected to the lower body of the system while the second electrode is connected to the upper body. Both electrodes are connected to a pulse generator. Each electrode has a sample contact surface such that the first electrode and the second electrode may be positioned to hold a surface tension constrained sample between the two sample contact surfaces and the sample may receive a selected electric pulse.

System and method for electroporating a sample

The present invention provides improved methods of attenuating gene expression through the phenomenon of RNA interference. The invention provides methods of synthesis of double stranded RNAs (dsRNAs) of increased potency for use as small interfering RNA (siRNA). Surprisingly and unexpectedly, siRNAs made by the methods of the invention are significantly more potent than previously available siRNAs.

High potency siRNAS for reducing the expression of target genes

Growing community of inventors

Austin, TX, United States of America

Richard A Jarvis