Zoll Circulation, Incorporated

Concentric Medical, Inc.

Cardiothoracic Systems, Inc.

Richard A Helkowski

Jeremy Thomas Dabrowiak

Alex L Lim

Venkata Vishnu Gurukula

James Adam Palazzolo

Gary A Freeman

Ivan Sepetka

Masouneh Mafi

Mark Glenn Mitchell

William N Aldrich

Martin S Dieck

John Miller

Ryan Pierce

Masoumeh Mafi

John Thomas Buckley

Anna Grace Prestezog

Michael V Morejohn

Byron J Reynolds

Maureen Bensing

Diana Sanchez

George L Walls

David Trevor Lawrence

Melanie Lynn Harris

Ari Manoukian

Paolo Giacometti

James Palazzolo

The present disclosure provides systems for controlling infusion of one or more supplements into blood received from a patient. The systems include at least one an extracorporeal circulatory support system including a pump, fluid conduits, and at least one a sensor configured to measure one or more parameters of the blood. The system also may include a fluid flow regulator coupled to the extracorporeal circulatory support system. The system receives measurement signals corresponding to parameters of blood from the at least one sensor and determines one or more target values for the parameters of blood based on a patient profile and/or the measurements. The system may control the fluid flow regulator to cause an infusion of at least one supplemental fluid from a supplemental fluid source into the blood.

Automated fluid infusion control for circulatory support and ECMO systems

A method of reducing the likelihood of shivering comprises monitoring at least one physiological characteristic in a human or animal subject to detect preshivering and acting to reduce the likelihood of shivering when preshivering is detected.

Detecting and responding to preshivering

A catheter includes a working fluid supply path communicating with a source of working fluid. The catheter also includes a working fluid return path communicating with the working fluid supply path to return working fluid from the supply path to the source of working fluid. At least one of the paths is contained in a distal heat exchange region of the catheter, where the distal heat exchange region includes first and second helical paths and is made of a shape memory material.

Patient temperature control catheter with helical heat exchange paths

A system includes a heat exchange catheter line assembly configured to convey working fluid circulating to and from at least one heat exchange element on an intravascular heat exchange catheter. The system also includes a heat exchange system that itself includes a processor and is configured for fluidly communicating with the heat exchange catheter line assembly to exchange heat with the working fluid. A near filed communication (NFC) member associated with the heat exchange system and an NFC element associated with the heat exchange catheter line assembly are also included. The NFC member is configured to provide the processor with a signal representative of whether the NFC member detects the NFC element.

Intravascular heat exchange catheter and system with RFID coupling

An intravascular heat exchange catheter has serpentine-like supply and return conduits circulating working fluid with a heat exchange system to warm or cool a patient in which the catheter is intubated.

Intravascular heat exchange catheter with rib cage-like coolant path

A transatrial intravascular temperature management catheter has a lower heat exchange segment positionable in the inferior vena cava and an upper heat exchange segment positionable in the superior vane cava, with a connecting segment lying between the two and positionable in the right atrium. A temperature sensor on the distal tip of the upper heat exchange segment provides accurate core body temperature signals for feedback purposes since the blood flowing past the sensor has not yet reached the heat exchange segment.

Transatrial patient temperature control catheter

A control system for an arterial catheter operable to selectively impede blood flow includes a processor and a storage medium accessible to the processor that bears instructions which when executed by the processor cause the processor to execute logic including receiving a first signal representing a physical parameter associated with a patient in whom the catheter is disposed, receiving a second signal representative of time, and causing inflation of a first balloon on the catheter to impede blood flow in the first artery. Based at least in part on the first signal satisfying a first condition, the instructions include causing deflation of the first balloon. Based at least in part on the second signal indicating elapse of a predetermined time period, the instructions include causing deflation of the first balloon regardless of whether the first signal satisfies the first condition.

Control system for arterial catheter

A system includes a heat exchange catheter line assembly configured to convey working fluid circulating to and from at least one heat exchange element on an intravascular heat exchange catheter. The system also includes a heat exchange system that itself includes a processor and is configured for fluidly communicating with the heat exchange catheter line assembly to exchange heat with the working fluid. A near field communication (NFC) member associated with the heat exchange system and an NFC element associated with the heat exchange catheter line assembly are also included. The NFC member is configured to provide the processor with a signal representative of whether the NFC member detects the NFC element.

A patient temperature control catheter () includes working fluid supply () and return () lumens through which working fluid circulates to exchange heat with a patient in whom the catheter is positioned. At least one lumen is defined by plural coils () axially spaced from each other. At least a first coil is a large coil that inflates with working fluid to seat against a wall of a blood vessel in which the catheter is positioned, with blood flowing through the coil so as not to block blood flow in the vessel. Alternate centering structures () are disclosed.

Self-centering patient temperature control catheter

A patient temperature control catheter includes working fluid supply and return lumens through which working fluid circulates to exchange heat with a patient in whom the catheter is positioned. At least one lumen is defined by plural coils axially spaced from each other. At least a first coil is a large coil that inflates with working fluid to seat against a wall of a blood vessel in which the catheter is positioned, with blood flowing through the coil so as not to block blood flow in the vessel.

A catheter has an inner sleeve through which refrigerant circulates to and from a source of refrigerant. The catheter also has an outer sleeve surrounding the inner sleeve, including a distal end thereof. The outer sleeve is filled with a frozen biocompatible substance. The refrigerant is separated from the biocompatible substance by one or more walls of the inner sleeve such that the refrigerant is isolated from a patient in whom the catheter is positioned by both the inner sleeve and the frozen biocompatible substance. The refrigerant circulates through the catheter when the catheter is positioned in the patient to maintain the biocompatible substance frozen as heat is transferred from the patient to the biocompatible substance.

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Redwood City, CA, United States of America

Richard A Helkowski