Fisons Ltd.

Richard A Appleton

John Dixon

David N Hardern

Sidney C Burford

David J Wilkinson

John R Bantick

David Johnston

Kevin Brown

Kevan Brown

There are disclosed compounds of the formula (I): ##STR1## in which the variables R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, and X are defined in the specification. The compounds are useful as pharmaceuticals, especially as anti-inflammatory agents.

Anti-inflammatory 4-aminophenyl derivatives

There are described compounds of formula I, ##STR1## in which either R.sub.2 represents hydrogen, alkyl or Ar.sub.2, and

Anti-inflammator 1,n-diarylpyrazol-3-amines

There are described compounds of formula I, ##STR1## in which R.sub.1 represents hydrogen, alkyl, alkanoyl or alkyl substituted by Ar.sub.1,

Pyrazole-3-amines as anti-inflammatory agents

There are described compounds of formula I, ##STR1## in which R.sub.1 is phenyl substituted by halogen, alkoxy, alkyl, carboxy-alkyl, --NR.sub.4 R.sub.5, carboxy or alkoxy carbonyl,

3,4-Dihydro-3-oxopyrido[2,3-b]-pyrazines, compositions and use thereof

There are described compounds of formula I, ##STR1## in which Ra is hydrogen, alkyl, alkenyl or phenyl, R.sub.3, R.sub.5, R.sub.7 and R.sub.8, which may be the same or different, are each hydrogen, alkyl, alkoxy, halogen, hydroxy, alkenyl or phenyl,

2-(4H-1-Benzopyran-6-yl)propionic acids

There are described compounds of formula I, ##STR1## in which Ra is hydrogen, alkyl, alkenyl or phenyl,

Growing community of inventors

Leicestershire, United Kingdom

Richard A Appleton