Other

Gh Care Inc.

Diabcell Pty Ltd

Diabell Pty Ltd.

Università Degli Studi Di Perugia

Gh Care, Inc. D/b/a Altucell, Inc.

Riccardo Calafiore

Robert Bartlett Elliott

Giuseppe Pietro Pio Basta

Gusseppe Basta

Francesca Mancuso

Pia Montanucci

Giovanni Brotzu

Paolo Puccetti

Giovanni Luca

Mario Calvitti

Ennio Becchetti

Francesca Fallarino

Claudio Nastruzzi

A membrane including a barrier having layers of alginate with different material molar concentrations relative to another material. The layers have a uniform consistency across a thickness of the layers. The thickness is free of laminae and interfaces and forms a single layer morphology that provides permeability for selected molecules.

Alginate microcapsules for cell and molecular therapy that secrete bioactive immune molecules

A method for microencapsulation includes isolating myofibroblasts from Wharton's jelly of a human umbilical cord. The myofibroblasts are microencapsulated using ultra-purified sodium alginate, wherein the myofibroblasts encapsulated in the sodium alginate form a three-dimensional spherical structure.

Clinical grade sodium alginate for microencapsulation of myofibroblasts isolated from wharton jelly for prevention and treatment of autoimmune and inflammatory diseases

The invention relates to the use of Sertoli cells (SC) microencapsulated into hydrogel-based microcapsules, for the prevention and/or treatment of Type 1 diabetes mellitus (T1DM) and to a process for producing microcapsules, preferably shaped as microspheres.

Microencapsulation process of sertoli cells, microcapsules obtained and use for treatment of type I diabetes mellitus

A process for the ultrapurification of alginates is provided. In particular, the process may be used for microencapsulation in human cell transplants.

Process for the ultrapurification of alginates

The invention relates to developments in the treatment of diabetes in mammals. Particularly it relates to a method of preparing a xenotransplantable porcine islet preparation capable upon xenotransplantation of producing porcine insulin in an appropriate recipient mammal, the method including or comprising the steps of: Further, the invention relates to a method of encapsulation of a xenotransplantable porcine islet preparation, and transplantation of such a preparation, or a capsule containing such a preparation, into an appropriate recipient mammal.

Preparation and xenotransplantation of porcine islets

A vascular prosthesis having a low porosity outer material such as PTFE, and an inner synthetic tubular mesh. Semi-permeable microcapsules that contain hormone-producing cells, are placed between the outer material and the inner mesh. The microcapsules are preferably made of polysaccharides or amino-acid polymers.

Vascular prosthesis containing in the wall microcapsules, including

A vascular prosthesis having a low porosity outer material such as FTFE, and an inner synthetic tubular mesh. Semi-permeable microcapsules that contain hormone-producing cells, are placed between the outer material and the inner mesh. The microcapsules are preferably made of polysaccharides or amino-acid polymers.

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Perugia, Italy

Riccardo Calafiore