Duke University

The United States Government as Represented by the Department of Veterans Affairs

Ricardo Henao Giraldo

Geoffrey S Ginsburg

Christopher W Woods

Ephraim L Tsalik

Thomas W Burke

Rachel A Myers

Joseph E Lucas

Micah T McClain

Erik Soderblom

The present disclosure provides methods and systems for processing a nucleic acid sample. The present disclosure also provides methods and systems for detecting (e.g., optically detecting) a pathogen in a sample. The methods provided herein may use nucleic acid amplification.

Methods and systems for processing a nucleic acid sample

The present disclosure provides methods for determining the presence or absence of and/or the etiology of an acute respiratory viral infection in a subject, as well as methods of treating the subject based on the determination, by measuring on a platform the expression levels of a pre-defined set of gene products.

Nasopharyngeal protein biomarkers of acute respiratory virus infection and methods of using same

The present disclosure provides methods for determining whether a subject has sepsis, or is at risk of developing sepsis, and methods of treating the subject based on the determination. Also provided are methods for determining an increased risk of mortality in a subject with sepsis or suspected of having sepsis, and methods of treating the subject based on the determination. Systems useful for the same are also provided.

Gene expression signatures useful to predict or diagnose sepsis and methods of using the same

Growing community of inventors

Durham, NC, United States of America

Ricardo Henao Giraldo