Teva Pharmaceutical Industries Limited

Revital Ramaty

Revital Lifshitz-Liron

Yuriy Raizi

Shlomit Wizel

Gideon Pilarski

Ariel Mittelman

Sharon Avhar-Maydan

Nurit Perlman

Amihai Eisenstadt

Nada Kosutic Hulita

Marina Kalujny

Esti Marom

Solid state forms of Sitagliptin salts (e.g. Sitagliptin sulfate, Formula I), processes for preparing the solid state forms, and pharmaceutical compositions thereof, are provided. These compounds are of a class of dipeptidyl peptidase IV enzyme inhibitors which are useful, for example, for the manufacture of a medicament for the treatment of type 2 diabetes mellitus. 

Solid state forms of sitagliptin salts

Isolated cinacalcet carbamate, processes for the preparation thereof, and processes for the use of cinacalcet carbamate as a reference marker and standard are provided. Also provided are cinacalcet salts substantially free of cinacalcet carbamate, and processes for the preparation thereof.

Purification of cinacalcet

Processes for preparing cinacalcet are provided.

Process for preparing Cinacalcet hydrochloride

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Ramat-Hasharon, Israel

Revital Ramaty