Other

Wavelength Enterprises Ltd

Perrigo Api Ltd.

Revital Ben-Daniel

Ronny Neumann

Alexander Khenkin

Itai Adin

Sonia Krivonos

Gloria Ten Figas

Alex Weisman

Yevgeny Rozenblat

Ana Fernandez Casares

Ana Fernadez Casares

Provided are ibrutinib polymorphs, e.g., crystalline ibrutinib Forms III, IV, V, VI, VII, VIII and Form IX and processes for producing these crystalline forms, stable amorphous ibrutinib and processes for preparing stable amorphous ibrutinib, pharmaceutical compositions comprising these forms and methods of using these crystalline and amorphous forms.

Ibrutinib solid forms and production process therefor

The invention provides a process for the catalytic epoxidation of an alkene comprising a transition metal substituted polyoxofluorometalate and molecular oxygen with the alkene. The invention also includes transition metal substituted polyoxofluorometalates of the formula Q &lsqb;NaH (TM)(H O)M F O &rsqb; and the molecular structure depicted in FIG. , where M is Mo, W, Nb, V or combinations thereof, TM is selected from Ti, V, Cr, Mn Fe, Co, Ni, Cu, Zn and the noble metals Ru, Pd, Rh, Ir, Os and Pt,, and Q is a countercation countering the charge q , and a process for preparing such polyoxofluorometalates.

Process for the epoxidation of alkenes and polyoxofluorometalates for use therein

The invention provides a process for the catalytic epoxidation of an alkene comprising contacting a transition metal substituted polyoxofluorometalate and molecular oxygen with said alkene.

Polyoxofluorometallates and use thereof as catalysts for the epoxidation of alkenes

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Modiin, Israel

Revital Ben-Daniel