Merck Sharp + Dohme Corp.

Revathi Reddy Katipally

Pengcheng Patrick Shao

Feng Ye

Jian Liu

Wanying Sun

Petr Vachal

Deyou Sha

Brian Alexander McKittrick

Sung-Sau So

Paul E Finke

Jianming Bao

F Anthony Romero

Feroze Ujjainwalla

Zhicai Wu

John S Debenham

Harold B Wood

Peter Orth

Ashwin Umesh Rao

Weiguo Liu

Joseph Leslie Duffy

Jacqueline D Hicks

Brent Whitehead

Ping Lan

Sathesh P Bhat

Sriram Tyagarajan

Debra L Ondeyka

Jerry Andrew Taylor

Edward C Sherer

Yi Zang

Markus Kristofer Dahlgren

Zahid Hussain

Remond Moningka

Zhongxiang Sun

Hong Dong Chu

Matthew Lombardo

Aaron Zwicker

Patrick Shao

Michael A Plotkin

Jayanth Thiruvellore Thatai

Amy Bittner McCracken

Joseph L Duffy

Jonathan E Gable

Sujit Kumar Sarkar

Amy Bittner Mccracken

Brent R Whitehead

Zahid Hussian

Anthony Romero

The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIIa inhibitors. 

Factor XIIa inhibitors

Thiazolidinone compounds, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis.

Therapeutic thiazolidinone compounds

Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. 

Fused bicyclic oxazolidinone CETP inhibitor

Substituted spirocyclic amines of structural formula (I) are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as Type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, Metabolic Syndrome, depression, and anxiety. 

Spiroxazolidinone compounds

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Monmouth Junction, NJ, United States of America

Revathi Reddy Katipally