Depuy Synthes Products, Inc.

Csem Centre Suisse D'electronique Et De Microtechnique Sa

Mathys Ag Bettlach

Dr. H.c. Robert Mathys Stiftung

Reto Luginbühl

Marc Bohner

Robert Mathys

Thierry Stoll

Jürgen Vogt

Hans Sigrist

Beat Gasser

Giancarlo Rizzoli

Hendrik Van Den Vlekkert

Hui Chai-Gao

Yannick Loosli

Nigel Skinner

Jorge Luis Sague Doimeadios

A bone graft substitute in the form of an implantable three-dimensional scaffold that includes calcium phosphate and has pores. The scaffold is impregnated with a calcium and/or phosphate containing substance, and the dissolution rate DRof the scaffold is slower than the dissolution rate DRof the calcium and/or phosphate containing substance.

Bone graft substitute in the form of an implantable three-dimensional scaffold and method of manufacturing same

A kneadable and moldable bone-replacement material includes a mixture of calcium-containing ceramic particles and a hydrogel or a substance which can be swelled into a hydrogel. The ceramic particles are of fully synthetic origin and the individual ceramic particles have a structure which is at least partially cohesive and porous. In addition, the majority of the ceramic particles have a non-spheric shape.

Kneadable and pliable bone replacement material

The present invention is directed to an implant device, in particular an implant device placed between bony, cartilaginous or soft tissues or between prosthetic surfaces to restore or create a gap. More particular the present invention is directed to an implant device made from polymeric material and having a stiffness gradient as well as a limited dimensional deformation, wherein the implant device has a stiffness gradient and a limited dimensional deformation and preferably is at least partially anisotropic.

Implant device

The invention relates to a device including a substrate and at least one biologically active substance bound to at least a part of the surface of this substrate, which is obtained by simultaneous or sequential reaction of said substrate and of said substance with a bifunctional coupling agent in which one of the functional groups is capable of being photoactivated and generates carbenes and is used to bind the coupling agent to the inorganic substrate and the other functional group is used to bind the coupling agent to the biologically active substance, in which said substrate is a covalent inorganic nitride.

Device including a biologically active substance immobilized on a

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Spiez, Switzerland

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