Koninklijke Philips Corporation N.v.

René Van Den Ham

Bart Jacob Bakker

Hendrik Jan Van Ooijen

The present invention relates to device () for determining a fibrinogen level () in a sample () comprising, a first input for obtaining an attenuance signal () over time indicative of a fibrin polymerization of said sample (), a second input for obtaining a reactant concentration signal () over time indicative of a reactant concentration in said sample (), wherein the reactant is any substance leading to the cleavage of fibrinogen to fibrin, a simulation unit () running a model () using the reactant concentration signal () as an input to provide a simulated attenuance signal () over time, and an evaluation unit () configured to infer the fibrinogen level () of said sample () by comparing the attenuance signal () over time with the simulated attenuance signal () over time.

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Utrecht, Netherlands

René Van Den Ham