Syngenta Participations Ag

Syngenta Crop Protection Ag

Renshui Liu

Jeng Shong Chen

Kevin V Donohue

Richard Sessler

Guo-Qing Tang

Milan Jucovic

This invention provides polypeptides that were identified as interacting with Vip3 toxin. This invention also provides a method of identifying agents that bind to Vip3 interacting polypeptides, which agents may act as insecticidal agent, cytotoxic agents and/or modulate the activity of Vip3 interacting polypeptides.

Expression cassette and host cell for expressing a Vip3-interacting protein

Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, interfering RNA molecules that capable of interfering with pest histone genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants to confer protection from insect damage are disclosed.

Biological control of coleopteran pests

Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, dsRNA molecules that capable of interfering with pest IAP genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants to confer protection from insect damage are disclosed.

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Research Triangle Park, NC, United States of America

Renshui Liu