Boehringer Ingelheim Pharmaceuticals, Inc.

Renee L Des Jarlais

Joachim Heider

Mark R Player

James M Rinker

Charles Lawrence Cywin

Bao-Ping Zhao

Michael Peter Winters

Mark A Bobko

Scott E Jakes

Disclosed are compounds of formula (I): wherein R, R, Rand Rare defined herein, which are useful as inhibitors SYK kinase and are thus useful for treating diseases resulting from inappropriate mast cell activation, which include allergic and inflammatory diseases. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

1,6 Naphthridines useful as inhibitors of SYK kinase

1,6 naphthyridines useful as inhibitors of SYK kinase

1,6 Naphthyridines useful as inhibitors of SYK kinase

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St. Davids, PA, United States of America

Renee L Des Jarlais