Novasterilis, Inc.

Renee Christopher

Anthony Romey Eisenhut

David C Burns

Tim W Christensen

J Anastasia Kazenski

J Anastasia Nichols

A process for creating acellular donor soft tissue by removing contaminants such as cells by extraction using a fluid at supercritical temperature and pressures while preserving the integrity of the soft tissue. The soft tissue is maintained in contact with the fluid in a pressure vessel at supercritical temperature and pressures for a period of time and then the pressure vessel is rapidly depressurized.

Process for creating acellular viable donor soft tissue

A process for cleaning donor soft tissue by removing contaminants by extraction using a fluid at supercritical temperature and pressures while preserving the integrity of the tissue.

Method and apparatus for cleaning of viable donor soft tissue

The invention relates to a method for forming a molded article during sterilization and under high pressure utilizing a supercritical fluid as a sterilization fluid, whereby the pressurization and depressurization rates are controlled to form molded articles.

Preparation and sterilization of green state devices using a supercritical fluid sterilant

A method is disclosed that produces allografts from matrices typically containing demineralized bone matrix (DBM) powder, demineralized bone matrix gel, demineralized bone matrix paste, bone cement, cancellous bone, or cortical bone and mixtures thereof. The matrices are sterilized utilizing supercritical COin the presence of a sterilizing additive and an entrainer such as an alkaline earth metal compound, preferably CaCO. The resultant allograft materials have a reduced rate of rejection when used in allograft procedures including, bone, cartilage, tendon, and ligament grafting procedures.

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Dryden, NY, United States of America

Renee Christopher