Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V.

University of Southern California

Rene Seitz

Rainer Hintsche

Walter Gumbrecht

Reinhard Bredehorst

Clive R Taylor

Robert D MacPhee

The invention relates to a method for producing a detection system for detecting different analytes in a sample, characterised by the following steps: providing a planar or essentially planar substrate which has sensors for chemically, optically or electrically detecting the analytes; applying an already microstructured layer to the substrate or applying a continuous layer to the substrate and microstructuring said layer, the layer being applied in such a way in either case that the areas of the substrate that are separated from each other are not covered by the layer, the layer and substrate being sealingly interconnected at least around the uncovered areas; bringing at least some of the uncovered areas into contact with at least one liquid containing catcher molecules, in such a way that said catcher molecules are able to adhere or bond to the surface of the substrate and/or on the surface of the sensors; removing the non-adhering constituents of the liquid and removing the microstructured layer or parts thereof.

Method for producing detection systems with planar arrays

An immunochemical and molecular biologic endpoint reporter system in which reaction products, coupled to electrochemically active molecules susceptible to redox recycling or coupled to enzymes capable of proportional generation of said electrochemically active molecules, are detected and/or quantitated using amperiometry in conjunction with a silicon microchip possessing a closely spaced interdigitated array of nobel metal electrodes.

Electrochemical reporter system for detecting analytical immunoassay and molecular biology procedures

Growing community of inventors

Itzehoe, Germany

Rene Seitz