Dpx Holdings B.v.

Upfront Chromatography A/s

Rene Oehlenschlaeger Holte

Allan Otto Fog Lihme

Marie Bendix Hansen

Brian A Larsen

Allan Otto Lihme

Kurt Hauge Jensen

Tony Christensen

Brian Larsen

The present invention relates to a method for producing beads comprising a material capable of gelation, said method comprising the steps of: (i) combining (a) a liquid composition comprising a material capable of gelation; and (b) a first hydrophobic phase; (ii) subjecting the liquid composition and the first hydrophobic phase, to means for emulsification in a first reactor by addition of external mechanical energy creating an emulsion comprising individual droplets comprising the material capable of gelation in the first hydrophobic phase (wherein the material capable of gelation provides a discontinuous phase and the first hydrophobic phase provides a continuous phase); (iii) stabilizing the droplets by transferring the emulsion from the first reactor to a stabilization reactor wherein the emulsion obtained in step (ii) is subjected to means for gelation in order to obtain gelation within 5 minutes or less, and the beads are formed.

System and method for producing beads

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Soborg, Denmark

Rene Oehlenschlaeger Holte