Institut National De La Sante Et De La Recherche Medicale

Université Claude Bernard Lyon I

Inserm

René Ferrera

The present invention relates to an aqueous solution for organ preservation, in particular for the myocardium, the solution comprising:

Aqueous solution for preserving an organ and uses during hypothermic ischemia

A device for hypothermic perfusion of a cardiac organ comprising a first sealed tank able to contain a physiological liquid, a second sealed tank communicating, in a sealed manner, with an internal volume of the first tank via a nozzle, a device for refrigerating the first tank and keeping the first tank at a substantially constant temperature and a device for intermittently pressurizing the internal volume of the first tank. The first tank communicates with the pressurizing device by way of a conduit connecting an interior of the first tank to the pressurizing device to permit pressurization of the internal volume of the first tank, and of the physiological liquid inside the first tank, in order to perform perfusion of the organ. The second tank comprises a safety element formed by an overflow outlet duct which communicates with the first tank and includes a non-return valve.

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Decines, France

René Ferrera