Ab7 Innovation S.a.s.u.

Ab7 Innovations S.a.s.u.

Rene Chelle

Arnaud Vilbert

Aurelie Alba

Urbain Makoumbou

Giovanni Chabot

The subject-matter of the present invention is the use of a therapeutic composition comprising, in an applying carrier, at least one essential oil for relieving muscle and/or joint pain in an animal subject, wherein said composition topically treats an area of the skin of said subject, characterized in that said composition comprises methyl salicylate, which constitutes, with at least one essential oil of the composition containing same in only a small amount or not at all, an active agent within which the rate of transport of the methyl salicylate through the skin is increased by virtue of the oil, which is an essential oil.

Pain-killing composition comprising a salicylic acid derivative

The invention relates to a monopolymer multifunctional sequenced cast polyurethane matrix produced simply and efficiently, by sequentially pouring various isocyanate/polyol complex phase solutions successively into a mold with alternating solidification of said phase solutions according to a defined order and respecting the polymerization stage (after the pot life and before the demolding time) of the sequence preceding the one being cast, so as to end with the casting of the last phase solution that will go up to the demolding time thereof and thereby finish the polymerization of the whole of the matrix. It is loaded, in its 'reservoir' sequences, with naturally originating or synthesized transdermally penetrating or volatile active substances. They are medicating and therapeutic, cosmetic, phytosanitary or wellness substances, repellents, attractants, pheromones, biocides, perfumes or deodorants. At least two active substances can be loaded into the same matrix in order to act unidirectionally or in opposite directions. Said matrix is used to form different devices that adhere to the skin or any other surface, in order to deliver at least one substance in a controlled manner. Said devices are patches, patches with a plurality of active substances, replaceable plasters stuck to a textile support, active heel pads and ball pads for shoes, pheromone cards for controlling insects, self-adhesive insecticide attractant cards, or other devices equivalent in terms of structure and function.

Monopolymer multifunctional sequenced cast polyurethane matrix and production thereof

The invention relates to a solid inoculum carried in a superabsorbent agro-pellet with a variable volume, operating in a natural mini fermenter preloaded with an anhydrous nutritive medium, encouraging rapid regrowth of the viable micro-organisms and the continuous multiplication thereof. The liquid inoculum incorporated into the carrier at a low density of microbial cells is preferably comprised between 1/500e and 1/10e of the density recommended by the norm for a liquid inoculum of the same strain. The bioaugmentation of the microbial population is between 104 and 106 additional microbial cells. The solid inoculum according to the invention allows the preservation of the microorganisms and the handling thereof in advantageous conditions. It is not exposed to soil leaching caused by water. Said inoculum is used for the biological treatment of crops for the development and/or the preservation thereof from parasite attacks.

Solid inoculum carried in a superabsorbent agro-pellet with a variable volume, operating in a natural minifermenter, and production method

The invention relates to a monopolymer multifunctional sequenced cast polyurethane matrix produced simply and efficiently, by sequentially pouring various isocyanate/polyol complex phase solutions successively into a mould with alternating solidification of said phase solutions according to a defined order and respecting the polymerisation stage (after the pot life and before the demoulding time) of the sequence preceding the one being cast, so as to end with the casting of the last phase solution that will go up to the demoulding time thereof and thereby finish the polymerisation of the whole of the matrix. It is loaded, in its 'reservoir' sequences, with naturally originating or synthesised transdermally penetrating or volatile active substances. They are medicating and therapeutic, cosmetic, phytosanitary or wellness substances, repellents, attractants, pheromones, biocides, perfumes or deodorants. At least two active substances can be loaded into the same matrix in order to act unidirectionally or in opposite directions. Said matrix is used to form different devices that adhere to the skin or any other surface, in order to deliver at least one substance in a controlled manner. Said devices are patches, patches with a plurality of active substances, replaceable plasters stuck to a textile support, active heel pads and ball pads for shoes, pheromone cards for controlling insects, self-adhesive insecticide attractant cards, or other devices equivalent in terms of structure and function.

Monopolymer multifunctional sequenced cast polyurethane matrix and production method

The invention relates to the implementation of a method for loading, without a vehicle, a naturally crystalline substance solubilized by a solvent mixture in a lipophilic medium in a mixture of granulated polymers, for forming, without a plasticizer, a polymer support for the long-term controlled distribution of the naturally crystalline substance in the stable solubilized state, without permanent crystallization on the surface of said support. Said substance according to the invention can be insecticides and pesticides of the group of pyrethroids (e.g. deltamethrin), formamidines (e.g. amitraz) and carbamates (e.g. propoxur), or the mixture thereof, or cosmetics of the group of alkaloids (e.g. caffeine), or medicaments (e.g. ibuprofen). The permanent non-crystallization state on the surface of the polymer support is only ensured when said substance is solubilized in the solvent mixture consisting of an oxygenated solvent of dibasic esters of methylenic fatty acids and an oxygenated methylenic cosolvent in an active lipophilic solution incorporated into a polymer mixture consisting of a polyether block amide (PEBA) and a thermoplastic polyurethane elastomer (TPU). Said support can be shaped as a collar, as an ear tag for animals, a band, a patch, a tag, a polymer block or any other device for the distribution of the active substances. It is shaped by any one of the plastic processing techniques known by a person skilled in the art. It is advantageous in that it is loaded with a quantity of active substance of between 30% and 50% less than the previous devices for at least the same active efficiency.

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Crepiac, France

Rene Chelle