Jiangnan University

Ndsu-research Foundation

Ren Liu

Liping Zhang

Caihua Ni

Xinxin Sang

Jing Luo

Gang Wang

Gang Shi

Xiaoya Liu

Zhiquan Li

Jing Xu

Yu Liu

Zhigang Chen

He Liu

Dawei Wang

Shengwen Zhang

Yangyang Xu

Yuanyuan Ding

Xiaopeng Zhang

Xiaofeng Xia

Jingcheng Liu

Yiqun Yang

Chenglin Yi

Haiqiang Wu

Sisi Jiang

Baoqing Wang

Jinqiang Jiang

Junzhe Zhu

Xiucheng Zou

Yongqin Zhao

Zhenle Tian

Xinyi Dong

Jiatao Miao

The invention presents a near-infrared photothermal coupling curing non-oxide ceramic slurry, along with its preparation method and application. The ceramic slurry consists of various raw materials, with weight fractions as follows: non-oxide ceramic powder (40˜90 parts), photosensitive resin (0.5˜20 parts), photosensitive monomer (1˜40 parts), photoinitiator (0.25˜4 parts), thermal initiator (0.25˜4 parts), additive (0.75˜5 parts), and up-conversion luminescent material (0.5˜4 parts). The non-oxide ceramic powders can include SiN, TiN, BN, AlN, SiC, WC, TiC, ZrC, TiB, and ZrB. By combining the photochemical and photothermal dual curing system using near-infrared up-conversion, this invention addresses the issue of insufficient curing encountered in single photocuring or thermal curing processes. Moreover, by incorporating near-infrared light source-driven additive manufacturing, it enables rapid prototyping of high-solid-content non-oxide ceramic slurry, ultimately allowing for the fabrication of high-fidelity non-oxide ceramic structures.

Near-infrared photothermal coupling curing non-oxide ceramic slurry and its preparation method and application

A dark-colored system photopolymerization composition, comprising: 20-80 phr of photopolymerizable prepolymer, 5-60 phr of photopolymerizable monomer, 0.2-8 phr of photoinitiator, and 0.1-5 phr of melanin, 0.05-5 phr of upconversion materials. The composition can construct photopolymerization under near-infrared irradiation. The dark pigment can avoid the strong absorption of near-infrared light, and the upconversion material can absorb near-infrared light with good penetrating ability and emit ultraviolet or visible light to induce the decomposition of free radicals or ionic photoinitiators in the composition. Then produced active species realize the photopolymerization of dark-colored compositions. The invention increases the depth of photopolymerization of dark-colored compositions and improves the mechanical properties of the polymer, that will broaden application fields of photopolymerization materials.

Dark-colored system photopolymerized composition

The invention relates to an ink based on near-infrared light polymerization. The method and technology of direct writing three-dimensional printing belong to the field of material processing technology area. The method is: direct writing nozzles move in three-dimensional space or stationery, the ink is squeezed out of the direct writing nozzle, receiving the near-infrared light irradiation, after curing, complete the three-dimensional object forming and curing. The solidifying time t does not exceed the ratio of near-infrared light diameter dand the ink extrusion speed vi, that is, t≤d/v. Since near-infrared light has a better medium mass penetration, can penetrate the structure during molding to promote both internal and external to a higher degree of curing, so as to achieve cross-scale structure 3D printing, and the method provided by the present invention accurately controls solidifying process of the ink and therefore achieve the DIW array 3D structure real-time curing.

Direct ink writing three-dimensional printing method based on near-infrared photopolymerization

A method for making xanthan gum copolymer nanomicelles comprising: 1) degrading xanthan gum in aqueous solution to obtain degraded xanthan gum; 2) preparing xanthan gum bromide from the degraded xanthan gum; 3) preparing xanthan gum copolymer from the xanthan gum bromide and 4) making the gum copolymer nanomicelles from the xanthan gum copolymer. The xanthan gum copolymer nanomicelles have good morphological regularity, good biocompatibility and stable performance as an anticancer drug carriers.

Method for preparation of xanthan gum copolymer nanomicelles

A method of preparing degradable and environment responsive composite microgels, belonging to polymer material synthesis and biomaterial technology fields. Firstly, a copolymer of L-malic acid and 6-hydroxyhexanoate is prepared; then, N,N,N',N&#x2032;-tetramethyl cystamine is prepared. The copolymer and N,N,N&#x2032;,N&#x2032;-tetramethyl cystamine are mixed in an organic solvent to form a mixed solution which is added into excess distilled water to produce composite microgels. The microgels have advantages of mild preparing conditions, fast reaction speed without catalysts, no impurity remained, and controllable degradation rate. The microgels can load anticancer drug doxorubicin hydrochloride, showing environment responsive controlled release due to introduction of carboxyl groups and disulfide bonds.

Method of preparing degradable and environment responsive composite microgels

The invention discloses a preparation method of pH/reduction responsive polyamino acid zwitterionic nanoparticles, which belongs to the technical field of polymer synthesis and biomedical materials. In the invention aliphatic amines are used to initiate ring-opening polymerization of &#x3b3;-benzyl-L-glutamate-N-carboxylic anhydride, and the obtained poly(&#x3b3;-benzyl-L-glutamate) reacts with L-lysine to form azwitterionic polymer. The zwitterionic polymer is crosslinked by cysteamine, producing pH/reduction responsive polyamino acid zwitterionic nanoparticles after purification. The nanoparticles are pH responsive and resistant to non-specific protein adsorption. Because cysteamine contains disulfide bonds, the nanoparticles have sensitive reductive responsiveness and can load anticancer drugs for controlled release at the target site of cancer.

Method of preparing pH/reduction responsive polyamino acid zwitterionic nanoparticles

The present invention discloses modified epoxy acrylates and the solder resist containing the epoxy modified acrylates, belonging to the synthetic resin field. In this invention, modified epoxy acrylates are prepared by introducing long fatty hydrocarbon chain as the branched chain into the carboxylated epoxy acrylates. The as-prepared solder resist containing this modified epoxy acrylates maintains the excellent property of photosensitive solder resist such as good adhesion, hardness, solvent resistance and weather resistance which facilities sensitivity and alkaline development during exposure simultaneously. This has led to good water resistance, electrical insulation of the cured products. Furthermore, the cured product also shows good flexibility which improves its application in photosensitive imaging ink materials.

Preparation of modified epoxy acrylates and solder resist containing modified epoxy acrylates

Hybrid amphiphilic star copolymer nano micelles are prepared in the invention. Cage shaped octa(&#x3b3;-aminopropyl) silsesquioxanes is selected as the inorganic part, and L-glutamic benzyl ester&#x2014;five membered ring anhydride is ring-opening polymerized by the initiation of amino groups on the surface of cage shaped octa(&#x3b3;-aminopropyl) silsesquioxanes, producing copolymers with cage shaped octa(&#x3b3;-aminopropyl) silsesquioxanes as nucleus and poly (L-glutamic-benzyl ester) as arms. The copolymers reacts with monomethoxy poly (ethylene glycol) carboxylic acid by condensation. Finally, the benzyl groups in the side chains of poly (L-glutamic acid-benzyl ester) are converted into hydrazine groups by acylhydrazination to obtain hybrid amphiphilic star copolymer nano micelles. The micelles can load doxorubicin, they are safe to human body and have good application prospects.

Method for preparation of hybrid amphiphilic star copolymer nano micelles

Disclosed is a preparation method for charge reversal and reversibly crosslinked redox-sensitive nanomicelles, falling within the technical field of biomedical materials. The method comprises: synthesizing thiocinamide from lipoic acid and ethylenediamine under an N,N'-carbonyl diimidazole catalyst; and polymerizing thiocinamide, polyethylene glycol diglycidyl ether and lysine through a nucleophilic addition mechanism to prepare a poly(lysine-co-polyethylene glycol diglycidyl ether-co-thiocinamide) terpolymer. The micelle is endowed with excellent anti-protein nonspecific adsorption and enhanced cell uptake property through a self-assembly and protonation/deprotonation action; and a disulfide bond in lipoyl may form a linear polydisulfide structure under the action of 1,4-dithiothreitol, so that a micelle core is crosslinked, and a crosslinked structure is destroyed in the cell under a redox condition, and controlled release of a drug can be achieved. The Nanomicelle of the present invention is expected to be a carrier of drugs for treating cancers.

Preparation method for charge reversal and reversibly crosslinked redox-sensitive nanomicelles

The present invention discloses a triazine-containing photocurable resin and a preparation method thereof. The preparation method of the resin comprises the following steps of: (1) Dissolving the hexamethylolmelamine the unsaturated fatty acids and a catalyst in a solvent, keeping a reaction going, separating and extracting the reaction product after the reaction ends, obtaining triazine-containing fatty acid ester; (2) adding 50 wt % hydrogen peroxide, a catalyst and a solvent, namely methylbenzene, into the triazine-containing fatty acid ester prepared in step (1), keeping a reaction going, obtaining triazine-containing fatty acid ester epoxy resin; (3) adding a polymerization inhibitor and a catalyst into acrylic acid, dropping the triazine-containing fatty acid ester epoxy resin prepared in step (2), keeping a reaction going, and obtaining the triazine-containing photocurable resin. The photocurable resin of the present invention contains a rigid triazine and flexible fatty chains at the same time, so the cured object has excellent comprehensive performance and can be used as the photocurable resin in the field of photosensitive macromolecular materials.

Triazine-containing photocurable resin and preparation method thereof

Branched and hyperbranched oligomers and polymers that contain a cashew nutshell oil or liquid component are provided. The novel oligomers and polymers are suitable for use as an oil, lubricant, coating, adhesive, resin or composite.

Bio-based branched and hyperbranched polymers and oligomers

A preparation method for molecular recognition sensor by electrodeposition is provided. The preparation method is as following: forming molecularly imprinted polymeric micelles by self-assembly of ionic type photosensitive copolymers; forming a film on the surface of an electrode by electrodepositing the molecularly imprinted polymeric micelles at a constant potential; crosslinking the electrodeposited micellar film via ultraviolet light irradiation; extracting the template molecules from the crosslinked film to obtain electrode modified by the molecularly imprinted polymeric micellar film; and connecting the modified electrode with a sensor device and a computer to construct a molecular recognition sensing system capable of specifically detecting the template molecules.

Growing community of inventors

Jiangsu, China

Ren Liu