Ciba-geigy Corporation

Lonza Inc.

Ren E Imwinkelried

Jacques Gosteli

Karl-Heinz Altmann

Gareth J Griffiths

Albert Eschenmoser

Compounds of the formulae I and Ia and their racemates ##STR1## in which A is --CH.sub.2 -- or --CH.sub.2 CH.sub.2 --, R.sub.1 is hydrogen or a protective group, R.sub.2 is hydrogen or a protective group or a radical forming a phosphorus-containing nucleotide bridge group and B is a purine or pyrimidine radical or an analogue thereof, can be used as antiviral active ingredients or for the preparation of biologically active oligonucleotides.

Carbocyclic nucleosides containing bicyclic rings, oligonucleotides

2-Substituted 5-chlorimidazoles of the general formula: ##STR1## are new intermediate products for the production of antihyperintensive pharmaceutical agents or of herbicidal compounds. A process for the production of these intermediate products as well as a new process for the further reaction of 2-substituted 5-chlorimidazoles of general formula I, wherein R.sub.1 is hydrogen, to the 2-substituted 5-chlorimidazole-4-carbaldehydes of the formula: ##STR2##

Growing community of inventors

Brig-Glis, Switzerland

Ren E Imwinkelried