Centre National De La Recherche Scientifique

Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

National University of Singapore

Remi Galland

Vincent Studer

Manuel Thery

Jean-Christophe Gabriel

Jean-Baptiste Sibarita

Virgile Nicolas Robert Viasnoff

Laurent Blanchoin

Gianluca Grenci

A sample holding device for use in transverse illumination of a sample or sub-components of a sample comprising: a support substrate comprising a sample well adapted to contain and be compatible with said sample wherein said well is provided on at least one wall with an angled reflective surface adjacent said sample well which when in use directs a transverse light beam from a light source through a sample contained within said sample well to provide substantially transverse illumination of a sample contained therein and imaging the sample using a single objective.

Micro-textured surface with integrated micro-mirrors for 3D multi-scale microscopy

The present invention relates to a method for preparing three-dimensional actin structures having a well-defined shape and displaying improved mechanical rigidity. This method comprises the steps of (a) providing a polymerization solution comprising actin monomers, a branching agent and a capping agent, (b) providing at least one surface having thereon a pattern which is coated with a nucleating agent, and (c) contacting the at least one surface of step (b) with the polymerization solution of step (a) so as to induce the polymerization of actin and obtain the said desired three-dimensional actin structure. Applications of the present invention in various technological fields such as microelectronics are also provided.

Method for obtaining three-dimensional actin structures and uses thereof

Growing community of inventors

Singapore, Singapore

Remi Galland