Bayer Aktiengesellschaft

Bayer Intellectual Property Gmbh

Bayer Technology Services Gmbh

Reinhold Rose

Helmut Brod

Helmut Judat

Sebastian Schmidt

Peter Jähn

Georg Wiessmeier

Jörg Kauling

Martin Poggel

Bernhard Krumbach

Rainer Krautkrämer

Björn Frahm

Stefanie Köhler

Thomas Siebert

Wolfgang Hemmerle

Olaf Behrend

The invention relates to a reactor driven in an oscillatory-rotary manner about its fixed, preferably vertical, axis, for preferably biotechnological and pharmaceutical applications. By means of its process-intensifying properties for mixing, suspension, gaseous material transport, heat transfer, irradiation and particle retention, the applicability on the industrial scale is ensured. The reactor which succeeds without a shaft seal permits particularly robust production with respect to sterile technique with avoidance of cleaning and cleaning validation required when the reactor is constructed as a single-use reactor.

Eccentrically-rotating reactor

A mixer having improved axial and radial mixing which retains good mixing time even during large viscosity changes, comprising a housing with at least one helical or anchor agitator located centrally in the housing in combination with at least one eccentrically arranged screw or blade agitator, preferably in mutual engagement, the combination of a helical agitator and a screw agitator enabling a much shorter mixing time as compared to a mixer having only a helical agitator without a screw agitator.

Mixer having a centrally disposed helical or anchor agitator and eccentrically disposed screw or blade agitator

Modular device and method for carrying out experiments in parallel on process substances to develop technical methods, comprising at least a multiplicity of individual reactors which are controllable independently of one another said reactors being comprised of pressure-tight chambers having separable sample vessels, and optionally, stirring devices, heating instruments, cooling instruments, or both, a monitoring unit for monitoring or controlling at least the pressure and the temperature in the individual reactors, pressure-tight lids having independent feed lines and optionally independent discharge lines for individual process substances; a plurality of the lids being simultaneously sealable upon the rectors by a common sealing means ().

Device and method for carrying out experiments in parallel

An axial conveyor is described, in particular for conveying gas/liquid dispersions, wherein the conveying elements comprise a wall-sweeping edge pointing in the direction of the pressure side of the conveying elements. The axial conveyor is particularly suitable as a circulating member in loop reactors. A process comprising conveying gas/liquid dispersions as well as a process for carrying out chemical reactions directly reacting gas with gases not completely dissolved in a liquid medium, or optionally in the presence of finely divided solids, through the use of an axial conveyor, is also disclosed.

Axial conveyor and loop reactor containing said axial conveyor

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Leverkusen, Germany

Reinhold Rose