Dsm IP Assets B.v.

Nestec S.a.

Regina Goralczyk

Hasan Mohajeri

Ann Fowler

Goede Schueler

Antoine De Saizieu

Christof Wehrli

Claus Kilpert

Jonas Wittwer Schegg

Daniel Raederstorff

Joris Kloek

Ying Wang-Schmidt

Karin Wertz

Bernd Mussler

Damiet Josephina Petronella Cunera Koenders

Simone Koenig-Grillo

Nicolle Goetz

Jochen Klock

Henry Rieger

Jenny Piussi

Antione De Saizieu

Annis O Mayne-Mechan

Goede Schuler

Guillen Santiago Eusebio Fernandez-Reumann

Remo Graeub

Kathleen Simons

Marja Kanning

Christina Kalarickal

Leigh Gibson

Jonas Wittwer

Guido Alexander Van Wingen

Marijn Christoffel Waander Kroes

Stephane Etheve

Annis Olivia Mayne-Mechan

Loni Schweigert

Anne Eichinger

This invention is directed to the use of a protein hydrolysate, and in particular an egg lysozyme hydrolysate to assist an animal, including a human in overcoming an addition, or by breaking an unwanted habit.

Protein hydrolysates as agents to treat symptoms of addiction

Trp-containing peptides, preferably from hen's egg hydrolysate can increase the Cys levels in blood serum. This results in increased keratin production, and enhances growth, appearance, and/or volume in keratin-containing tissue including skin, hair, and/or nails.

Compositions comprising lysozyme hydrolysate for use in keratin-containing tissue

This invention relates to a method of increasing a feeling of a) energy or b) cognitive functions, selected from the group consisting of: sustained attention, faster reaction times, and information processing; or c) quality of sleep; or d) feelings of well-being and happiness in a healthy adult using a dosage form comprising a low dose of a Trp-containing di- and/or tri-peptide mixture characterized in that the peptide composition is an egg iysozyme hydroiysate with a Trp/L!MAA ratio greater than 0.15 and which provides IQ-to 100 mg Trp per dose. This dosage form can be administered acutely or can be administered multiple times per day for an extended period of time.

Use of tryptophan rich protein hydrolysates

The invention relates to the use of an oral composition comprising steviol, a steviol precursors orextract as skin tanning agent. It further relates methods of enhancing the natural skin tan by oral administration of an effective amount of Steviol, a Steviol precursor orextract.

Methods for enhancing skin tan and reducing risks of UV skin damage

Methods of enhancing the appearance of a mammal's hair/fur are provided by the administration of an oral nutraceutical or food composition comprising steviol or a steviol precursor, without chromene, for a time sufficient and in an amount effective to enhance the overall appearance of the mammal's hair/fur. The enhancement of the appearance of the mammal's hair/fur includes restoring hair/fur color, lessening hair loss, increasing the thickness of hair, counteracting age-associated hair thinning, and delaying the onset or severity of age-associated hair loss and thinning. A nutraceutical or food which includes steviol or a steviol precursor in an amount sufficient to enhance the overall appearance of a mammal's hair/fur is also provided.

Stevia extract or steviol for hair care

The present invention refers to tricyclic diterpenes and their derivatives of the formulae (I) and (II), wherein Ris hydrogen or C-alkyl; Ris hydroxy, C-acyloxy, hydroxymethyl, 1,3-dihydroxypropyl or C-alkyl; Rand Rindependently from each other are hydrogen, hydroxy, hydroxymethyl, C-acyloxy or C-alkoxy; Ris C-alkyl, hydroxymethyl carboxy or methoxycarbonyl; Ris hydrogen, hydroxymethyl, methoxy, oxo or C-acyloxy; Ris hydrogen, or Rand Rtaken together are &#x2014;CH&#x2014;O&#x2014; or &#x2014;O&#x2014;CH&#x2014;; or Rand Rtaken together are &#x2014;CO&#x2014;O&#x2014;, &#x2014;O&#x2014;CO&#x2014;, &#x2014;CH&#x2014;O&#x2014; or &#x2014;O&#x2014;CH&#x2014;; Ris hydrogen, or Rand Rtogether to form a bond; Rand Rindependently from each other are C-alkyl, carboxy, x-hydroxy-Cx-alkyl (with x being an integer from 1 to 6), or C-alkoxycarbonyl with the proviso that at least one of Rand Ris C-alkyl; Rand Rare both hydrogen or Rand Rtogether are oxo, with the further proviso for formula (I) that if Ris hydroxy Ris C-alkyl, for use as medicaments for the treatment of a disorder connected to impaired neurotransmission, as well as to dietary and pharmaceutical compositions and their uses.

Dietary and pharmaceutical compositions containing tricyclic diterpenes and their derivatives and their uses

The present invention refers to tricyclic diterpenes and their derivatives of the formulae (I) and (II), wherein Ris hydrogen or C-alkyl; Ris hydroxy, C-acyloxy, hydroxymethyl, 1,3-dihydroxypropyl or C-alkyl; Rand Rindependently from each other are hydrogen, hydroxy, hydroxymethyl, C-acyloxy or C-alkoxy; Ris C-alkyl, hydroxymethyl carboxy or methoxycarbonyl; Ris hydrogen, hydroxymethyl, methoxy, oxo or C-acyloxy; Ris hydrogen, or Rand Rtaken together are &#x2014;CH&#x2014;O&#x2014; or &#x2014;O&#x2014;CH&#x2014;; or Rand Rtaken together are &#x2014;CO&#x2014;O&#x2014;, &#x2014;O&#x2014;CO&#x2014;, &#x2014;CH&#x2014;O&#x2014; or &#x2014;O&#x2014;CH&#x2014;; Ris hydrogen, or Rand Rtogether form a bond; Rand Rindependently from each other are C-alkyl, carboxy, x-hydroxy-Cx-alkyl (with x being an integer from 1 to 6), or C-alkoxycarbonyl with the proviso that at least one of Rand Ris C-alkyl; Rand Rare both hydrogen or Rand Rtogether are oxo, with the further proviso for formula (I) that if Ris hydroxy Ris C-alkyl, for use as medicaments for the treatment of a disorder connected to impaired neurotransmission, as well as to dietary and pharmaceutical compositions and their uses.

Dietary and pharmaceutical compositions containing tricyclic diterpenes and their derivates and their uses

The present invention refers to carnosol and rosmanol for use (as medicament) in the treatment of a disorder connected to reduced neurotransmission, cognitive dysfunction and/or symptoms caused by headache and/or migraine, as well as to dietary and pharmaceutical compositions and their uses.

Dietary and pharmaceutical compositions containing carnosol and/or rosmanol and their uses

The present invention refers to coumarin ethers of the formula (I), wherein Ris H, OH or (E)-3-methyl-but-2-enyl, Ris selected from the group consisting of methyl, 3-(4,5-dihydro-5,5-dimethyl-4-furanon-2-yl)-2-(E/Z)-butenyl, (E/Z)-3,7-dimethylocta-2,6-dienyl, 7-hydroxy-3,7-dimethyl-2-octen-6-on-yl and (E/Z,E/Z)-11-acetyl-oxy-3,7,11,11-tetramethyl-undeca-2,7-dien-10-on-yl, Ris H, Rand RO together for the group &#x2014;O&#x2014;C(C(&#x2550;CH)CH)H&#x2014;CH&#x2014;O&#x2014; or the group &#x2014;C(H)&#x2550;C(H)&#x2014;C(CH)&#x2014;O&#x2014; or RO and Rtogether form the group &#x2014;O&#x2014;C(H)(C(CH)(H)&#x2014;O&#x2014;C(O)CH)&#x2014;CH&#x2014;, preferably to obliquin, for use as medicaments, especially for the treatment and/or prevention of disorders connected to impaired neurotransmission, as well as to dietary and pharmaceutical compositions and plant extracts containing such coumarin ethers and their uses.

Agents for preventing and treating disorders connected to impaired neurotransmission

The present invention refers especially to 3,5-dihydroxy-2,4-cyclohexadienones of the general formula (I) wherein Rand Rare independently from each other C-alkyl, C-alkenyl or x-oxo-C-alkyl with x being an integer from 1 to 6, preferably Rand Rare independently from each other C-alkenyl or y-oxo-C-alkyl with y being an integer from 2 to 5, and wherein Rand Rare independently from each other hydroxy, C-alkyl, C-alkenyl or x-oxo-C-alkyl with x being an integer from 1 to 6, preferably Rand Rare independently from each other hydroxy or y-oxo-C-alkyl with y being an integer from 2 to 5, for use as mood balancing agents and stress relievers, as well as to dietary compositions and fortified food/feed/beverages containing such 3,5-dihydroxy-2,4-cyclohexadienones of the general formula (I), and their uses. 

3,5-dihydroxy-2,4-cyclohexadienones and their derivatives, dietary compositions and fortified food containing them and their uses

Growing community of inventors

Grenzach-Wyhlen, Germany

Regina Goralczyk