Johns Hopkins University

Refaat Gabr

Paul Arthur Bottomley

Yi Zhang

Robert G Weiss

A method of performing spatially localized magnetic resonance spectroscopy includes receiving a magnetic resonance image of an object; identifying a plurality C of compartments that generate magnetic resonance spectroscopy signals in the object including at least one compartment of interest; segmenting in at least one spatial dimension the magnetic resonance image of the object into the C compartments; acquiring magnetic resonance spectroscopy signals from the compartments by applying a plurality of M' phase encodings applied in the at least one spatial dimension, wherein M&#x2032;&#x2265;C; calculating a spatially localized magnetic resonance chemical shift spectrum from the at least one compartment of interest; and rendering a spatially localized magnetic resonance spectrum that is substantially equal to a spatial average of magnetic resonance chemical shift spectra from the at least one compartment of interest. A magnetic resonance spectroscopy and imaging system is configured to perform the above method.

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Baltimore, MD, United States of America

Refaat Gabr