Kimberly-clark Worldwide, Inc.

Rebecca Ann Vongsa

David William Koenig

Amy Lynn Vanden Heuvel

Cathleen Mae Uttecht

Michael Andrew Zawadzki

Douglas Robert Hoffman

David Andrew Moline

Jeffrey Janne Johnson

Paige N Hollmaier

Lindsay Adrienne Peed

Cheryce Francina Joyner

Jingru Li

Corey Thomas Cunningham

Donald Eugene Waldroup

Lisa Marie Kroll

Paige N Anunson

Jeremy David Paulsen

Ryan Daniel Bartell

Dave Allen Soerens

Andrew Mark Long

Peiguang Zhou

David John Tyrrell

Stacy Averic Mundschau

Shiming Zhuang

SangHa Park

Alphonse Carl DeMarco

YoungSook Kim

Jessica Caroline Rogers

Corey T Cunnington

Youngsook Kim

Sangha Park

Alphonse C Demarco

The present invention relates to compositions, particularly compositions useful in maintaining and supporting healthy microflora in the female urogenital tract which could lead to inhibition of vaginal infections, as well as methods of treating and preventing vaginal infections. Compositions useful in supporting healthy microflora, disclosed herein, generally comprise a therapeutic amount of a first saccharide and a therapeutic amount of a second saccharide or an organic acid. The saccharides may be, for example, a pentose, a disaccharide, a cyclodextrin, a pectic substance or a non-digestible polysaccharide. The organic acid may be, for example, malic acid.

Synergistic composition for maintenance of healthy balance of microflora

A disinfectant composition that is capable of inactivating non-enveloped viruses as well as other microorganisms, such as gram negative and gram positive bacteria, fungi, parasites, enveloped viruses, etc., is provided. Through selective control over the nature of the acid(s) employed and the overall pH level, the present inventors have discovered that the composition can achieve rapid antiviral efficacy, particularly against non-enveloped viruses. Once applied to a surface (e.g., hard surface), the disinfectant composition forms a film that remains capable of providing residual antiviral activity. Notably, the present inventors have discovered that the use of a vinylpyrrolidone copolymer in combination with a polyquaternary ammonium polymer and cationic surfactant can have a synergistic effect on the stability of the film such that it can also achieve long-term, residual antiviral activity.

Residual disinfectant composition

The present invention relates to compositions, particularly compositions useful in maintaining and supporting healthy microflora in the female urogenital tract which could lead to inhibition of vaginal infections, as well as methods of treating and preventing vaginal infections. Compositions useful in supporting healthy microflora, disclosed herein, generally include a first therapeutic agent including α methyl-D glucoside and a second therapeutic agent including a nitrogen containing compound at a therapeutic amount. In some embodiments, the nitrogen containing compound can be, for example, L-Cysteine, Cytidine, D-Asparagine, Pyrimidine, D-Alanine, D-Glucosamine HCL, and N-Acetyl-D-Glucosamine.

The present invention relates to prebiotic compositions and formulations comprising an &#x3b1;-hydroxy acid and salts thereof, such as lactic, glycolic, citric, tartaric or malic acid and a prebiotic agent, such as inulin, fructo-oligosaccharide (FOS), lactulose, galacto-oligosaccharide (GOS), raffinose, stachyose, isomalto-oligosaccharide, and xylo-oligosaccharide. Prebiotic compositions of the present invention provide a surprisingly synergist prebiotic effect and may be administered in several forms to a user, such as by application to a premoistened wiping substrate or dry bath tissue.

Synergistic prebiotic composition

The present invention relates to compositions having durable antimicrobial activity. The compositions include a carbonate/bicarbonate salt of a quaternary ammonium cation, an organic acid, hydrogen peroxide and a polymer. The polymer is selected from cationic amine polymer-epichlorohydrin adduct, cationic amine polymer-epichlorohydrin resin, poly(methacrylamidopropyltrimethylammonium) chloride, poly(bis(2-chloroethyl)ether-alt-1,3-bis(dimethylamino)propyl)urea, poly(diallyldimethylammonium) chloride, poly(t-butyl acrylate co-ethyl acrylate co-methacrylic acid), polyethylene oxide, polyquaternium-16, polyquaternium-22, polyquaternium-67 and mixtures thereof.

Durable antimicrobial composition

The invention relates to creped prebiotic tissue products. The tissue products comprise prebiotics in sufficiently high amounts to have a prebiotic effect in use, without negatively affecting tissue product properties, such as tensile strength, stiffness or softness. Thus, in certain embodiments the present invention provides soft, durable creped prebiotic tissue products that are able to improve the growth of healthy bacteria such asspp. orspp. without promoting growth of enteropathogenic bacteria. The tissue products provide these benefits yet have a GMT greater than about 500, a Stiffness Index less than about 20 and a TS7 value less than about 10.

Creped prebiotic tissue

A laminate having health-benefit agents therein is made by particle stabilization within the lamination process. By changing the substrate type (tissue, nonwoven, film) and/or the physical composition and/or attributes of the laminate layers, the release of the health-benefit agents can be controlled. The laminate, sometimes referred to as a liner, may be used in personal absorbent articles such as diapers, feminine pads, bandages, bed pads, and the like.

Article with health-benefit agent delivery system

Growing community of inventors

Neenah, WI, United States of America

Rebecca Ann Vongsa