University of Southern California

Minipumps, LLC

Children's Hospital Los Angeles

Syntouch, LLC

Raymond Peck

Jason Shih

Changlin Pang

Gerald E Loeb

Sean Caffey

Mark Salman Humayun

Yu-Chong Tai

Fukang Jiang

Nicholas Wettels

Steven Nutt

Yaniv Bar-Cohen

Veronica J Santos

Li Zhou

Jeremy Fishel

Jeffrey David Brennan

Jeffrey O Brennan

Po-Ying Li

Jeremy A Fishel

Ricardo G Hahn

Chia-Hsien Lin

Blaine Matulevich

Vikram Pandit

Chia Hsien (Gary) Lin

Lynda Marie Knox

Michelle Journey

The present invention provides an advancement in the art of cardiac pacemakers. The invention provides a novel and unobvious pacemaker system that comprises at least one pacemaker and that is, to a large extent, self-controlled, allows for long-term implantation in a patient, and minimizes current inconveniences and problems associated with battery life. The invention further includes a mechanism in which at least two pacemakers are implanted in a patient, and in which the pacemakers communicate with each other at the time of a given pacing or respiratory event, without any required external input, and adjust pacing parameters to respond to the patient's need for blood flow. The invention further provides a novel design for a pacemaker in which the pacemaker electrode is connected to the pacemaker body by a lead that is configured to allow the pacemaker to lie parallel to the epicardial surface and to reduce stress on the pacemaker and heart tissue.

Epicardial lead design

The present invention provides advancements in the art of cardiac pacemakers. The invention provides a pacemaker system that comprises at least one pacemaker and that is, to a large extent, self-controlled, allows for long-term implantation in a patient, and minimizes current inconveniences and problems associated with battery life. The invention further includes a mechanism in which at least two pacemakers are implanted in a patient, and in which the pacemakers communicate with each other at the time of a given pacing or respiratory event, without any required external input, and adjust pacing parameters to respond to the patient's need for blood flow. The invention further provides a design for a pacemaker in which the pacemaker electrode is connected to the pacemaker body by a lead that is configured to allow the pacemaker to lie parallel to the epicardial surface and to reduce stress on the pacemaker and heart tissue.

In various embodiments, a tool is employed in filling a drug-delivery device. The tool may include, for example, a needle that is admitted through a fill port of the drug-delivery device.

Implantable drug-delivery devices, and apparatus and methods for filling the devices

Elastomeric check valves for use, e.g., in small pump devices, may include a molded elastomeric valve body forming a pocket that extends from an opening at the valve inlet to a terminus inside the valve body, and having a slit extending from the terminus to a valve outlet.

Molded and packaged elastomeric check valve

Embodiments of an implantable electrolytic pump include a drug reservoir, a cannula fluidly coupled to the reservoir, a pumping mechanism for forcing liquid from the reservoir through the cannula, control circuitry for operating the pumping mechanism, and a power source comprising primary and auxiliary batteries in a stacked configuration, only the main battery being operatively coupled to the control circuitry during normal operation, the control circuitry operatively coupling the back-up battery upon detection of an electrical fault. The pump may further include a hermetic enclosure containing the control circuitry and the power source.

Drug-delivery pumps and methods of manufacture

A compliant tactile sensor may include sponge-like material, a flexible skin, and a fluid pressure sensor. The flexible skin may have a shape, absorb fluid, compress in response to force applied to the sponge-like material, and decompress and return to its original shape when the force is removed. The flexible skin may cover an outer surface of the sponge-like material. The fluid pressure sensor may sense changes in pressure in fluid that is within the sponge-like material caused by a force applied to the flexible skin. A robotic system may include a movable robotic arm, a compliant tactile sensor on the movable robotic arm that senses contact between the compliant tactile sensor and an object during movement of the movable robotic arm and that cushions the effect of that contact, and a reflex system that causes the moveable robotic arm to move in response to commands.

Compliant tactile sensor with fluid-filled, sponge-like material

Tactile sensors are disclosed that mimic the human fingertip and its touch receptors. The mechanical components are similar to a fingertip, with a rigid core surrounded by a weakly conductive fluid contained within an elastomeric skin. The deformable properties of the finger pad can be used as part of a transduction process. Multiple electrodes can be mounted on the surface of the rigid core and connected to impedance measuring circuitry within the core. External forces deform the fluid path around the electrodes, resulting in a distributed pattern of impedance changes containing information about those forces and the objects that applied them. Strategies are described for extracting features related to the mechanical inputs and using this information for reflexive grip control. Controlling grip force in a prosthetic having sensory feedback information is described. Techniques are described for enhancing the useful force range for impedance sensors by internally texturing the elastomeric skin.

Enhancements to improve the function of a biomimetic tactile sensor

Tactile sensors are disclosed that mimic the human fingertip and its touch receptors. The mechanical components are similar to a fingertip, with a rigid core surrounded by a weakly conductive fluid contained within an elastomeric skin. The deformable properties of the finger pad can be used as part of a transduction process. Multiple electrodes can be mounted on the surface of the rigid core and connected to impedance measuring circuitry within the core. External forces deform the fluid path around the electrodes, resulting in a distributed pattern of impedance changes containing information about those forces and the objects that applied them. Strategies are described for extracting features related to the mechanical inputs and using this information for reflexive grip control. Controlling grip force in a prosthetic having sensory feedback information is described. Pressure transducers can provide sensory feedback by measuring micro-vibrations due to sliding friction.

Measurement of sliding friction-induced vibrations for biomimetic tactile sensing

Implantable drug-delivery pump

An infant positioner and positioning system, and methods of use and manufacture, are disclosed for preventing SIDS, plagiocephaly, torticolli, or suffocation from regurgitation. The device and system includes an infant positioner with a concave back support and abdominal support for positioning an infant on its side. A position marker can also indicate how to position the infant within the infant positioner.

Infant safety system

Growing community of inventors

Los Angeles, CA, United States of America

Raymond Peck