Hologic, Inc.

Raymond Jenoski

Ryan P Oliva

Michael Cordeiro

Eric E Grimes

Barry F Hunt

Michael D Quick

Robert Jennings

Sid Mayer

John A McCrorey

Sarah Margaret Harrington

An automated system for processing a sample contained in a liquid sample container includes an automated tool head configured to rotate about a first axis, and to translate along a second axis different than the first axis, an analytic element positioner having an analytic element holder configured to releasably grip an analytic element, and a specimen transfer device carried by the tool head, wherein the tool head is configured to automatically position a working end of the specimen transfer device to obtain a specimen from a sample container held in the sample container holder, and to transfer the obtained specimen to an analytic element held by the analytic element holder, respectively, through one or both of rotation of the tool head about the first axis and translation of the tool head along the second axis.

Systems for automated preparation of biological specimens

Automated systems and methods for evaluating specimens affixed to substrates, such as slides, an exemplary system including a slide imager configured for acquiring a plurality of micro images of a specimen affixed to an substrate, the specimen including a plurality of objects distributed within a three-dimensional volume, and for generating a whole specimen image of the specimen using the micro images, wherein objects contained in the specimen are depicted substantially in focus in the whole specimen image regardless of a z-depth of the respective objects within the specimen. The whole specimen image is stored on a storage medium for subsequent review by a cytotechnologist using a computer-controlled review station including a display and a user interface, wherein the review station user interface is configured such that the cytotechnologist can review and classify the stored whole specimen images.

Digital imaging system and method

An automated specimen preparation system for preparing a specimen from a sample in a sample container is provided. The automated specimen preparation system comprises a specimen transfer device configured for holding a specimen collector thereon and for being positioned within the sample container. The specimen transfer device comprises a central bore having an open distal end and a closed proximal end, a pressure monitoring port fluidly coupled to the central bore at the proximal end of the central bore, and a fluid waste evacuation port fluidly coupled to the proximal end of the central bore. The pressure monitoring port comprises a reduced diameter portion coupled directly to the central bore. The automated specimen preparation system further comprises a vacuum source fluidly coupled to the fluid waste evacuation port, and a pressure monitoring device fluidly coupled to the pressure monitoring port.

Growing community of inventors

Boylston, MA, United States of America

Raymond Jenoski