Merial Limited

Rhone Merieux

Raymond E Hopponen

Lowell R Macy

James B Williams

Roger A Wilson

Water miscible pharmaceutical compositions containing up about 40% of a marcrolide such as an azalide antibiotic are prepared by reaction of the macrolide with acid in a non-aqueous water miscible organic solvent system.

Water miscible macrolide solutions

Water miscible pharmaceutical compositions containing up to about 40% of a macrolide antibiotic are prepared by reaction of the macrolide with acid in a non-aqueous water miscible organic solvent system.

Water miscible pharmaceutical compositions containing up to about 40% of erythromycin prepared by reaction with acetic acid in a non-aqueous water miscible organic solvent system.

Water miscible erythromycin solutions

Aqueous pharmaceutical compositions containing up to about 40% spectinomycin, prepared by the reaction of the ketone hydrate of spectinomycin with boric acid to form the boron compound, and with a base such as sodium hydroxide to form the stable salt of the compound.

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Fort Dodge, IA, United States of America

Raymond E Hopponen