Monsanto Company

Diffusion Pharmaceuticals LLC

Pfizer Corporation

Hemagen/pfc

Other

Raymond C Grabiak

Dennis Patrick Riley

John L Gainer

Donald L Fields, Jr

Robert J Kaufman

Robert K Howe

Thomas J Richard

William P Cacheris

Sherrol L Baysdon

Karl E Koenig

John Gregory Slatter

Len F Lee

Thomas Edward Rogers

Peter E Rogers

David E Schafer

Lowell R Smith

James A Miles

Jr Fields

Cheryl Yearell-Vinson

Albert C Lee

The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.

Bipolar trans carotenoid salts and their uses

Novel 3,3-diphenylpropylamines of the formula and stereoisomers and physiologically acceptable acid addition salt thereof; wherein R, R, R, R, R, and Rare as defined herein; methods of use thereof; and pharmaceutical compositions thereof.

3,3-diphenylpropylamines useful in therapy

Novel 3,3-diphenylpropylamines of the formula  and stereoisomers and physiologically acceptable acid addition salt thereof; wherein R, R, R, R, R, and Rare as defined herein; methods of use thereof; and pharmaceutical compositions thereof.

A process for preparing glyphosate and other secondary amines of related structure in which a precursor primary amine such as aminomethylphosphonic acid is condensed with glyoxylic acid, or a related aldehyde compound, and the condensation product reduced without isolation to produce the desired product.

Process for the preparation of glyphosate and glyphosate derivatives

Emulsions of paramagnetic contrast agents, and processes of making and using them are disclosed. The emulsions contain water, a dispersed oil phase and a complex of a paramagnetic metal ion and an organic acid chelator, for example DTPA (diethylenetriaminepentaacetic acid), having a C.sub.10 -C.sub.30 saturated aliphatic group and an hydroxyl group bonded to the nitrogen atom. The emulsions are very stable and therapeutically acceptable for intravenous administration to enhance MRI imaging.

Paramagnetic complexes of N-alkyl-N-hydroxylamides of organic acids and

Emulsions of paramagnetic contrast agents, and processes of making and using them are disclosed. The emulsions contain water, a dispersed oil phase and a complex of a paramagnetic metal ion and an organic chelator having a C.sub.10 -C.sub.30 unsaturated aliphatic group. The emulsions are very stable and therapeutically acceptable for intravenous administration to enhance MRI.

Emulsions of paramagnetic contrast agents for magnetic resonance imaging

A process for the production of N-phosphonomethylglycine comprising contacting N-phosphonomethyliminodiacetic acid with a peroxide in the presence of a catalyst selected from the group consisting of the salts and salt complexes of cobalt and vanadium, and an effective amount of a quinone or hydroquinone.

Process for producing N-phosphonomethylglycine

A process for the production of N-phosphonomethylglycine comprising contacting N-phosphonomethyliminodiacetic acid with a peroxide in the presence of a catalyst selected from the group consisting of the salts and salt complexes of cobalt and vancadium, and an effective amount of dipyridyl compound.

Process for producing N-phosphonomethylgylcine

2-Amino-4,5-disubstituted-oxazole/thiazole compounds and antidotes for thiocarbamate, triazine and acetamide herbicides. These antidote compounds are especially effective to safen acetamide herbicides used to control grassy weeds in sorghum and broadleaf weeds in corn.

2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide

A process for the production of N-phosphonomethylglycine comprising contacting N-phosphonomethyliminodiacetic acid with a molecular oxygen-containing gas in the presence of a catalyst selected from the group consisting of the salts and salt complexes of manganese, cobalt, iron, nickel, chromium, ruthenium, aluminum, moleybdenum, vanadium and cerium, and an effective amount of a dipyridyl compound.

Growing community of inventors

Maryland Heights, MO, United States of America

Raymond C Grabiak