University of Houston System

University of Texas System

Indiana University

Other

University of Rochester

Advanced Research & Technology Institute

Raymond A Applegate

Larry N Thibos

Arthur Bradley

Konrad Pesudovs

Jason D Marsack

David R Williams

Yue Shi

Provided herein is a computer program product comprising a non-transitory computer-readable medium storing an algorithm to optimize a wavefront guided correction for a custom ophthalmic lens. The correction is determined from inputs of quantified wavefront error and registration uncertainty and a metric predictive of a visual performance task of interest and provides a level of visual performance within a user-defined performance range. Also provided is a method for optimizing a wavefront guided correction for a custom ophthalmic lens via inputting residual wavefront error values and quantified translational and rotational movements into an algorithm configured to determine the optimal wavefront guided correction therefrom and a custom ophthalmic lens comprising the correction.

Method and algorithm for designing custom optics

Provided herein are methods of manufacturing an optical lens using image simulation and/or predictive metrics to determine optical aberrations and an iterative algorithm to correct the aberrations to create a custom-designed surface for the optical lens and to implement the manufacture of the custom-designed surface onto the lens. Also, a computer program product storing the method is provided. In addition, there are provided a customized optical lens designed by the method and a method of correcting optical aberration to improve visual using the customized optical lens. Further provided is a method of manufacturing a custom lens effective to mimic a subset of optical aberrations.

Method for designing and manufacturing custom optics

An method and system for determining the appropriate refractive prescription in a clinical optometry or opthalmology setting. Data in the form of aberrometric input, patient history and other information, and/or other environmental data is used to optimize a real-world prescription for an individual's optic needs through the use of a equivalent quadratic fitting calculation or a simulated through focus experiment.

System and method for optimizing clinical optic prescriptions

Several metrics to predict the subjective impact of the eye's wavefront aberrations are presented. The metrics can be based on RMS wavefront errors or slopes, the area of the critical pupil, a curvature parameter, the point spread function, the optical transfer function, or the like. Other techniques include the fitting of a sphero-cylindrical surface, the use of multivariate metrics, and customization of the metric for patient characteristics such as age.

Metrics to predict subjective impact of eye's wave aberration

A method for classifying a patient's eye includes the steps of:

Method of filtering data for the objective classification of eyes

Methods, systems, and media relating the display of scattering and/or absorption characteristics of an optical medium. For scattering measurements, a Hartmann-Shack calibration image of a measurement system is acquired to define a first plurality of point spread functions. A Hartmann-Shack test image of the medium is acquired to define a second plurality of point spread functions. A shift is determined between the test image and the calibration image. A point spread of each of the second plurality of point spread functions is measured, each of the second plurality of point spread functions including a component due to optical aberration of the medium and a component due to scatter. The component due to optical aberration is determined using the shift. The component due to optical aberration is deconvolved to determine the component due to scatter. A display of the local scattering characteristics is generated using the component due to scatter. For absorption measurements, a plurality of spot intensity measurements are acquired of a medium, each spot intensity measurement including a component due to reflectivity and a component due to absorption. The component due to reflectivity is determined, and the component due to absorption is determined.

Methods and systems for measuring local scattering and aberration properties of optical media

Vascular entoptoscope

Described herein are an apparatus and range of techniques used to study the retinal vasculature near the fovea, a description of the need and rationale for noninvasive in vivo monitoring of the retinal vasculature, a presentation of theoretical and practical considerations which demonstrate that entoptic visualization of the smallest capillaries near the fovea is optimized by a small short wavelength source (1 mm or less) rotating at 3.5 Hz in a circular path (radius 2 mm) imaged in the plane of the eye's entrance pupil and a discussion of the feasibility of using these techniques as a rese

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Kingwood, TX, United States of America

Raymond A Applegate