Ohemo Life Sciences, Inc.

Inspirion Delivery Sciences, LLC

Galderma S.a.

Oheno Life Sciences, Inc

Cerolife LLC

Cerovene, Inc.

Othemo Life Sciences, Inc.

Ray J DiFalco

Manish S Shah

Stefan Aigner

Nathalie Wagner

Jean-Pierre Etchegaray

Orally administrable pharmaceutical compositions, methods of administration, and methods of making the same are provided. The pharmaceutical compositions provide abuse deterrent properties.

Abuse deterrent compositions and methods of use

An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.

Abuse resistant forms of extended release oxymorphone, method of use and method of making

Abuse resistant forms of immediate release oxymorphone, method of use and method of making

Abuse resistant forms of extended release hydrocodone, method of use and method of making

Abuse resistant forms of immediate release hydromorphone, method of use and method of making

An oral pharmaceutical composition in unit dosage form comprising: (1) a first portion comprising: an active ingredient and a pH-dependent component, and (2) a second portion comprising a pH-raising agent is provided. Methods of administering the composition are also provided.

Pharmaceutical compositions comprising a pH-dependent component and pH-raising agent

Abuse resistant forms of extended release morphine, method of use and method of making

Orally administrable pharmaceutical compositions and methods of administration are provided. The pharmaceutical compositions provide abuse deterrent properties.

Orally administrable compositions and methods of deterring abuse by intranasal administration

Orally administrable compositions comprising calcium, methods of administration, and methods of making the same.

Orally administrable compositions comprising calcium

The present invention is directed to a pharmaceutical composition in unit dose form for orally delivering doxycycline to a human, the pharmaceutical composition comprising: a capsule, wherein the capsule is coated with a delayed release layer; wherein the delayed release layer comprises about 4 to 6 mg of doxycycline monohydrate and a binding agent, and wherein the delayed release layer is coated with an enteric coating; wherein the enteric coating dissolves at pH of about 5 to 6, and wherein the enteric coating is coated with an immediate release layer; wherein the immediate release layer comprises about 32 mg of doxycycline monohydrate and a binding agent, wherein the relative mean Cof the pharmaceutical composition is within 80.00% to 125.00% of a Cvalue of 510&#xb1;220.7 ng/mL, after administration of a single dose of the pharmaceutical composition to humans in a fasting state; and wherein the relative mean AUCof the pharmaceutical composition is within 80.00% to 125.00% of a AUCvalue of 9227&#xb1;3212.8 ng&#xb7;hr/mL, after administration of a single dose of the pharmaceutical composition to humans in a fasting state.

Growing community of inventors

Ridgewood, NJ, United States of America

Ray J DiFalco