International Minerals & Chemical Corp.

Ravi Viswanathan

Randolph B DePrince

Mohamad D Shalati

A device for the continuous administration of a diffusible agent having a relatively rapid rate of diffusion and a diffusible agent having a relatively show rate of diffusion comprises:

Device for the extended delivery of diffusible agents

The present invention relates to a delivery device designed to be implanted in an animal and for the administration of a stabilized growth promoting formulation. This device has a wall formed at least in part by a porous membrane which surrounds and defines a reservoir. The reservoir contains a growth promoting hormone and a stabilizer. Examples of such stabilizers include certain polyols, amino acids, polymers of amino acids having a charged side group at physiological pH, and choline salts.

Delivery device for the administration of stabilized growth promoting

A device for the continuous administration of a beneficial agent to a living being at a substantially steady rate which comprises:

Layered, compression molded device for the sustained release of a

Porcine serum albumin stabilizes porcine growth hormone, and provided for sustained release of porcine growth hormone in implant devices for swine.

Stabilized porcine growth hormone

A mixture comprising a dispersion of a water-diffusible solid in a solution of a non-aqueous solvent and a substantially water-insoluble polymer is formed. The non-aqueous solvent is removed from the mixture to substantially dry the mixture, and the substantially dry mixture is comminuted to form particles. A plurality of the particles are formed under pressure to produce a pellet suitable for use as a sustained release implant device.

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Terre Haute, IN, United States of America

Ravi Viswanathan