University of Rochester

Raul Andres Guevara-Torres

Jesse Schallek

Aby Joseph

A method to image an in vivo object in an eye includes illuminating an object in the eye by a light source; configuring one or more detectors to receive light from a conjugate plane behind a confocal plane of the object, the conjugate plane acting as a light screen; receiving at the one or more detectors a backscattered light from the light source which has been refracted at least in part by the object before being backscattered from the light screen to provide a detector data; and processing the detector data over a time period by a computer to generate information about the object.

In vivo object identification, counting, and imaging based on light backscattered from a plane behind the object

A method for imaging vertebrate translucent retinal structures includes: imaging a translucent retinal structure at a first imaging plane in the retina with a light source focused at such first imaging plane, and detecting reflected light with a non-confocal off-axis detector, wherein the detector is axially displaced from a plane conjugate to the first imaging plane to a plane conjugate to a reflective layer deeper in the retina along a path of illumination from the light source.

Label-free contrast enhancement for translucent cell imaging by purposefully displacing the detector

An ophthalmic imaging system for imaging an axial and lateral point-spread of light distribution pattern of light reflected from a surface of an animal or human eye includes an ophthalmic imaging apparatus adapted to generate an illumination light of a surface of the eye. A detection arm includes a digital micromirror device (DMD) having an array of mirror facets. A first detector is disposed to receive a first portion of the axial and lateral point-spread of light distribution of light, and one or a plurality of additional detectors are disposed to receive a light from one or a plurality of different portions of the axial and lateral point-spread of light distribution pattern of light. A detection arm, a method for imaging axial and lateral point-spread of light distribution components, and a method for auto-centering a distribution pattern in an imaging plane of a DMD device are also described.

Growing community of inventors

Rochester, NY, United States of America

Raul Andres Guevara-Torres