University of California

Ratneshwar Lal

Preston B Landon

Alexander Mo

Sungho Jin

Chulmin Choi

Zhaowei Liu

Qian Ma

Joon Bok Lee

Taekyoung Kim

Gennadi V Glinskii

Jaeyun Moon

Michael Taeyoung Hwang

Youngjin Kim

Qingqing Yang

Srinivasan Ramachandran

Brian Meckes

Kyungjun Hwang

Gunwoo Kim

Preston Boone Landon

Disclosed is an atomic force microscopy system includes a laser source configured to generate an optical probe beam containing light of different spectral light components at different optical wavelengths, a dispersive optical device positioned to receive the optical probe beam and configured to disperse the optical probe beam into different dispersed light beams that are at different optical wavelengths and are spatially separated from one another, a cantilever array including a plurality of cantilevers structured to detect a sample and configured to deflect the different dispersed light beams by moving in position based on an interaction with the sample to produce multiple deflected output beams at different output optical wavelengths from the cantilevers, and a plurality of photodetectors to receive the multiple deflected output beams of different wavelengths from the cantilevers, respectively.

Array atomic force microscopy for enabling simultaneous multi-point and multi-modal nanoscale analyses and stimulations

Methods, systems, and devices are disclosed for fabricating and implementing nanoscale and microscale structured carriers to provide guided, targeted, and on-demand delivery of molecules and biochemical substances for a variety of applications including diagnosis and/or treatment (theranostics) of diseases in humans and animals. In some aspects, a nanostructure carrier can be synthesized in the form of a nanobowl, which may include an actuatable capping particle that can be opened (and in some implementations, closed) on demand. In some aspects, a nanostructure carrier can be synthesized in the form of a hollow porous nanoparticle with a functionalized interior and/or exterior to attach payload substances and substances for magnetically guided delivery and controlled release of substance payloads.

Nanostructured carriers for guided and targeted on-demand substance delivery

Methods, systems, and nano-sensor devices are disclosed for detecting or discriminating nucleic acids with a single nucleotide resolution based on nucleic acid strand displacement. The detection can be made by time-lapse fluorescence measurements or by electro-based graphene FET, which can be combined with wireless communication to provide real-time transmission of the detected signals.

Nano-sensors for nucleic acid detection and discrimination

Disclosed are nanostructured materials that reflect light in selected spectra incorporated in dark colored textiles or substrates. In one aspect, a light reflecting material includes a textile exhibiting a dark color and formed of a plurality of fibers, and nanostructures arranged on the fibers and formed of a plurality of nanoparticles, the nanostructures having a dimension size of substantially less than &#xbd; of a visible light wavelength, in which the nanostructures reflect light from the textile or substrate in at least one of infrared, near-infrared, or red visible light spectra.

Sunlight reflecting materials and methods of fabrication

Growing community of inventors

La Jolla, CA, United States of America

Ratneshwar Lal