Zumutor Biologics Inc.

Rashmi Sharma

Maloy Ghosh

Sunit Maity

Vivek Halan

Sanghamitra Bhattacharjee

Kavitha Iyer Rodrigues

Bharath Ravindra Shenoy

Sahana Bhima Rao

Divya Unnikrishnan

Sankaranarayanan Srinivasan

Anuradha Hora

Karthika Nair

Sohang Chatterjee

Bhargav Prasad

Aswini Thanigaivel

Ashvini Kumar Dubey

Yogendra Manjunath Bangalore Muniraju

Sathyabalan Murugesan

Bairavabalakumar Natarajan

Subhra Prakash Chakrabarty

Anurag Tiwari

Santosh Kumar

Veeresha Kamanagowda

Amir Khan

Pravin Kumar Dakshinamurthy

Pavithra Mukunda

Shivani Patel

Ankurina Sharma

Amol Maliwalave

Nikitha Markanda

Nikitha M

Maliwalave Amol

Yogendra Manjunath Muniraju

The present disclosure relates to vectors for cloning and expressing genetic material including but not limiting to antibody gene or parts thereof and methods of generating said vectors. Said vectors express the antibody genes in different formats such as Fab or scFv as a part of intertransfer system, intratransfer system or direct cloning and expression in individual display systems. In particular, phage display technology is used to clone and screen potential antibody genes in phagemid which is followed by the transfer of said genes to yeast vector for further screening and identification of lead molecules against antigens. The present vectors have numerous advantages including uniquely designed inserts/expression cassettes resulting in efficient and smooth transfer of clonal population from phage to yeast vectors resulting in efficient library preparation and identification of lead molecules.

Vectors for cloning and expression of proteins, methods and applications thereof

The present disclosure relates to a method of generating an antibody library, not limiting to a synthetic antibody gene expression library built on pool of consensus nucleic acid sequences by using codon replacement technology. The present disclosure also relates to a synthetic antibody library generated by employing the method of the present disclosure and application(s) of said antibody library.

Method of generating a synthetic antibody library, said library and application(s) thereof

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Uttarakhand Haridwar, India

Rashmi Sharma