University of Pennsylvania

Bio-logic Systems Corp.

Raquel E Gur

Steven Siegel

Karen Winey

Robert H Lenox

Ruben Gur

Sushma S Trivedi

Surgically implantable drug delivery systems for long-term delivery of haloperidol containing a biodegradable polymer and haloperidol fabricated into the surgically implantable drug delivery systems via solvent casting and compression molding are provided. Also provided are methods for producing the surgically implantable drug delivery systems and methods for using these systems in the treatment of psychotic disorders such as schizophrenia.

Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use

A method and apparatus for evaluating physiological and behavioral functioning of predetermined regions of interest of the human brain by displaying topographical maps of measured information. Brain electrical activity and/or predetermined physical parameters are measured in association with selected neuropsychological tests, and the measured information is operated on by providing weighted output signals characteristic of physiological functioning of the regions of interest of the patient's brain. The resulting weighted output signals are plotted as a topographical map. The measured brain electrical activity and measured predetermined physical parameters are also compared and a conversion matrix developed based on data bases of measured information for normal and abnormal subjects.

Topographical mapping of brain functionality from neuropsychological

Growing community of inventors

Philadelphia, PA, United States of America

Raquel E Gur