Commissariat a L'energie Atomique Et Aux Energies Alternatives

Biomerieux, Inc.

Raphaël Mathey

Mathieu Dupoy

Pierre Joly

Pierre Marcoux

Frédéric Mallard

Armelle Novelli-Rousseau

A method for observing a sample is provided. The method includes the steps of: a) providing a volume (G, V) of a substantially transparent medium having a first refractive index (n) and having a first surface (S) that is convex, rounded, or faceted, and a second substantially planar surface (S), the first surface separating the volume from a surrounding medium (MA) having a second refractive index (n) that is lower than the first index, the sample to be observed being contained inside the volume or being deposited on the first surface; b) observing the sample through the second substantially planar surface; and c) determining the presence of a substance or an object in the sample by detection during step b), a ring of light that correlates with the volume.

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Grenoble, France

Raphaël Mathey