Novoste Corporation

Other

Best Vascular, Inc.

Emory University

Advanced Medical Sharps, Inc.

Raphael F Meloul

Richard A Hillstead

Jonathan J Rosen

Charles E Larsen

Thomas D Weldon

Ian R Crocker

Ron Waksman

Martin B Tobias

George K Bonnoitt, Jr

David S Halpern

Jennifer J McCrory

John A Santangelo

Richard L Walus

George K Bonnoit, Jr

Roelof Trip

Apparatus and method are described for delivery of a treating element, such as a radiation source, through a catheter to a desired site in the vascular system of a patient, such as a coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. The apparatus includes an elongated flexible catheter tube having proximal and distal end portions, with a lumen extending therebetween, and a diameter sufficiently small for insertion in to a patient's vascular system. One or more treating elements, such as a capsule or pellet containing radioactive material, is positionable within the lumen and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. A method for using such apparatus, including a method for using such apparatus simultaneously with a balloon angioplasty procedure, is disclosed.

Method and apparatus for treating a desired area in the vascular system of a patient

A safety needle includes a needle with a sharp end and a needle shield. The needle shield includes collapsible interlocking members, wherein one member is an end member with a hole surrounding the needle, a spring inside the collapsible interlocking members that applies an expanding force on the collapsible interlocking members, a releasable latch structure that retains the collapsible interlocking members in a collapsed state, wherein when the releasable latch structure is actuated the collapsible interlocking members expand and enclose the sharp end of the needle, and a closing structure that prevents the sharp end of the needle from exiting the hole after the collapsible interlocking members enclose the sharp end of the needle.

Safety needle and shield

A transfer device and catheter assembly for the delivery of treatment elements to a selected location within the intraluminal passageways of a patient as part of an intraluminal radiation system. The transfer device includes a gate member that permits the treatment elements to have the transfer device only if the catheter is attached thereto. A pressure indicator provides a visual indication of the fluid pressure within the transfer device, and provides for a release of the fluid if the pressure exceeds a predetermined pressure. The catheter also includes detents to secure it to the transfer device and which must be manually activated to remove the catheter from the transfer device. The transfer device includes circuiting that determines whether the treating elements reside within the transfer device based upon the reflectivity of the treating elements. A method for determining whether treating elements reside in the catheter is also disclosed.

Intraluminal radiation treatment system

Apparatus and method are described for delivery of a treating element, such as a radiation source, through a catheter to a desired site in the intraluminal passageways of a patient, such as a coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. The apparatus includes an elongated flexible catheter tube having proximal and distal end portions, with a lumen extending therebetween, and a diameter sufficiently small for insertion in to a patient's intraluminal passageways. One or more treating elements, such as a capsule or pellet containing radioactive material, is positionable within the lumen and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. A method for using such apparatus, including a method for using such apparatus simultaneously with a balloon angioplasty procedure, is disclosed.

Method and apparatus for radiation treatment of a desired area in the vascular system of a patient

This invention is a transfer device and catheter assembly for the delivery of treatment elements to a selected location within the intraluminal passageways of a patient as part of an intraluminal radiation system. The transfer device includes a gate member that permits the treatment elements to leave the transfer device only if the catheter is attached thereto. A pressure indicator provides a visual indication of the fluid pressure within the transfer device, and a pressure relief valve provides for a release of the fluid if the pressure exceeds a predetermined pressure. Transfer device also includes a treatment element detection system, low power indicator, a counter system, and an electromagnetic locking mechanism to prevent the opening or closing of the gate member when less than all of the treatment elements are in the transfer device.

An automatic fluid control having a first and second tube members and a slidable valve element capable of moving from a sealed closed position to an open position permitting fluid passage therethrough. In a preferred first embodiment, the elastomeric valve element is slidingly received with a passageway in the first tube. The valve element has a flange portion containing a plurality of slits that, when inverted and stretched, permit fluid to pass therethrough, but when closed, are in contact with the inner wall of the first tube and prevents fluid from passing therethrough. The valve element also can have a rigid plug attached within an opening in the top surface to present a preferably non-deformable contact point for a male luer tip, which, when pressed downward on the valve element, breaks a seal between the valve element and the first tube inner wall. In a second embodiment a toroidal shaped valve portion selectively forms a seal over a pin extending axially from the second tube member, the pin having a plurality of grooves in its surface to permit passage of fluid when the seal created by the valve element is broken. In a third embodiment, a valve element maintains a seal against a pin extending from the base of the second tube member and having a plurality of grooves. When the valve element is urged downward against the upward force of a spring, the pin grooves permit fluid flow through the second tube member.

Automatic fluid control valve

Catheter apparatus for radiation treatment of a desired area in the

Method and apparatus for treating a desired area in the vascular system

Growing community of inventors

Atlanta, GA, United States of America

Raphael F Meloul