Dsm IP Assets B.v.

Raphael Beumer

Werner Bonrath

Johannes Tschumi

Michael Gressly

Jonathan Alan Medlock

Franciscus Derks

Angela Wildermann

Chyi-Cheng Chen

Marc-André Mueller

Stefan Martin Stoeckli

Silke Dorn

Christine Mendrok

Philippe Emmanuel Maillan

Bettina Wüestenberg

Jochen Klock

Thomas Netscher

Christof Wehrli

Christine Mendrok-Edinger

Ulla Letinois

René Tobias Stemmler

Juergen H Vollhardt

Heinz Gutzwiller

Jocelyn Fischesser

Markus Nowotny

Ernst Zedi

Marcel Joray

Bernd Schlegel

Frank Eisele

Domenico Soriano

Hajo Lehmann

Jan-Marc Delpho

Franciscus Johannes M Derks

Processes for synthesizing new compounds that may usefully be employed in organic synthesis, especially in the synthesis of vitamin A or β-carotene and derivatives thereof, e.g. canthaxanthin, astaxanthin or zeaxanthin are disclosed. The new compounds are especially useful as intermediates (building blocks) in the synthesis of vitamin A or β-carotene, preferably vitamin A.

Intermediates for the vitamin A synthesis

The present invention relates to a process for the production of &#x3b2;-springene of formula (I) wherein a compound of formula (II) is heated in the presence of a catalyst. 

Process for the production of beta-springene

The present invention relates to novel compounds which are particularly useful for the synthesis of novel chromanol derivatives. These compounds have interesting properties. Particularly, the novel chromanol derivatives have interesting antioxidant properties as well as flavours and fragrances.

6-chromanol derivatives and their synthesis

The present invention relates to an improved process for the manufacture of 2,6-dimethyl-5-hepten-1-al.

Process for the manufacture of 2,6-dimethyl-5-hepten-1-al

The present invention relates to an improved way for the production of farnesol.

Production of farnesol

The invention relates to hair care compositions comprising an effective amount of a condensation polymer having at least one, optionally quaternized or protonated, dialkylamide end-group connected through the polymer backbone to a unit derived from an alkylamide, the connection comprising at least one ester linkage.

Hair care compositions

The present invention relates to an improved method for producing of 1-(5,5-dimethylcyclohex-1-en-1-yl)ethanone and 1-(5,5-dimethylcyclohex-6-en-1-yl)ethanone.

Process of production of 1-(5,5-dimethylcyclohex-1-en-1-yl)ethanone and 1-(5,5-dimethylcyclohex-6-en-1-yl )ethanone

The present invention relates to the use of a specific organic compound as flavor and fragrance material. Furthermore the invention relates to flavor and fragrance formulations comprising such a specific organic compound.

Flavor and fragrance formulation (V)

The present invention relates to the use of specific organic compounds as flavor and fragrance material. Furthermore the invention relates to new specific organic compounds, as well as to flavor and fragrance formulations comprising at least one of the specific organic compounds.

Flavor and fragrance formulation (III)

The present invention relates to the use of specific organic compounds as flavor and fragrance material. Furthermore the invention relates to a new specific organic compound, as well as to flavor and fragrance formulations comprising at least one of the specific organic compounds.

Flavor and fragrance formulation (II)

The present invention is directed to a process for the manufacture of methyl limonitrile comprising a mixture of 3,7-dimethyl-2,6-nonadiene nitrile, 3,7-dimethyl-3,6-nonadiene nitrile and 7-methyl-3-methylene-6-nonene nitrile comprising the following steps: a) reacting 6-methyl-5-octen-2-one with cyano acetic acid and removing carbon dioxide and water, wherein the reaction and the removal of carbon dioxide and water are performed in the presence of a base and a co-base 1 in an organic solvent, and wherein the organic solvent is a solvent which forms a heteroazeotrop with water; b) removing the solvent and the base of the reaction mixture obtained after having performed step a) or step c) by distillation to obtain a reaction mixture, whereby this step may optionally be performed in the presence of a co-base 2; c) isomerizing the reaction mixture obtained after having performed step a) or step b) to obtain an isomerized reaction mixture in the presence of a co-base 2; whereby step b) can be performed before or after step c).

Process for the manufacture of methyl limonitrile

The present invention relates to the use of specific organic compounds of formula (I) as flavor and fragrance material. Furthermore the invention relates to a new specific organic compound, as well as to flavor and fragrance formulations comprising at least one of the specific organic compounds.

Flavor and fragrance formulation (VI)

The present invention is directed to a process for the manufacture of methyl limonitrile comprising a mixture of 3,7-dimethyl-2,6-nonadiene nitrile, 3,7-dimethyl-3,6-nonadiene nitrile and 7-methyl-3-methylene-6-nonene nitrile comprising the following steps: a) reacting 6-methyl-5-octen-2-one with cyano acetic acid and removing carbon dioxide and water, wherein the reaction and the removal of carbon dioxide and water are performed in the presence of a base and a co-base in an organic solvent, wherein the base is pyridine, wherein the co-base is 1,4-diamino butane, and wherein the organic solvent is a solvent which forms a heteroazeotrop with water; b) removing the solvent and pyridine of the reaction mixture obtained after having performed step a) or step c) by distillation to obtain a reaction mixture; c) isomerizing the reaction mixture obtained after having performed step a) or step b) to obtain an isomerized reaction mixture; whereby step b) can be performed before or after step c).

The present invention relates to a new and improved synthesis of peretinoin.

Synthesis of peretinoin

The present invention relates to a new and improved synthesis of tetrahydromyrcenol (IUPAC name: 2,6-dimethyl-2-octanol).

Growing community of inventors

Basel, Switzerland

Raphael Beumer