Bristol-myers Squibb Compnay

Rao S Bhandaru

Karnail S Atwal

Heather J Finlay

John E Lloyd

Wayne D Vaccaro

Lin Yan

David R Kronenthal

Boguslaw Mudryk

Zhongping Shi

Novel heterocyclic dihydropyrimidine compounds useful as inhibitors of potassium channel function (especially inhibitors of the K1 subfamily of voltage gated Kchannels, especially inhibitors K1.5 which has been linked to the ultra-rapidly activating delayed rectifier Kcurrent I), methods of using such compounds in the prevention and treatment of arrhythmia and I-associated conditions, and pharmaceutical compositions containing such compounds.

Heterocyclic dihydropyrimidine compounds

Methods for the synthesis of benzodiazepine compounds having farnesyl protein transferase inhibitory activity.

Process for the preparation of 3,7-disubstituted-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine compounds

Novel heterocyclic dihydropyrimidine compounds useful as inhibitors of potassium channel function (especially inhibitors of the K 1 subfamily of voltage gated K channels, especially inhibitors K 1.5 which has been linked to the ultra-rapidly activating delayed rectifier K current I ), methods of using such compounds in the prevention and treatment of arrhythmia and I -associated conditions, and pharmaceutical compositions containing such compounds.

Growing community of inventors

Belle Mead, NJ, United States of America

Rao S Bhandaru