Arsenal Medical, Inc.

Transmural Systems LLC

The United States of America, As Represented by the Secretary, Department of Health and Human Services

480 Biomedical Inc.

Medtronic Vascular, Inc.

Telltale, Incorporated

Aresenal Aaa, Llc.

Lyra Therapeutics, Inc.

Zugates, Gregory T.

Freyman, Toby

Sharma, Upma

Busold, Rany

Miller, Lisette, Manrique

Rago, Adam

Rany Busold

Upma Sharma

Toby Freyman

Gregory T Zugates

Adam Rago

Parisa Zamiri

Irina Gitlin

Nasser Rafiee

Quynh P Pham

Changcheng You

Jeffrey D Carbeck

Robert J Caulkins

Stuart MacDonald

Lee A Core

Jennifer Mortensen

Robert J Lederman

Kicherl Ho

Toby Rogers

Nareak Douk

John Marini

Joseph Lomakin

Koosha Rafiee

Alexis Balcom

Maria Palasis

Morgan House

Daniel Concagh

Greg Zugates

Timothy Robinson

Jeffrey Groom, Ii

Danny Concagh

Lisette Manrique Miller

Janet Komatsu

My Le

Philipp Bonhoeffer

Juan-Pablo Mas

Jerry Brightbill

Benedict Shia

Stuart R MacDonald

Sarah Kostanski

Chang Cheng You

Michael Finney

Meghan McGill

Christopher G Bruce

Daniel K Bonner

John Caulkins

Changchen You

Kicheri Ho

The disclosure provides various embodiments of catheters having articulable ends that can be used for various procedures. Embodiments of methods are also provided that can be performed with catheters in accordance with the present disclosure.

Tissue excision, cutting, and removal systems and methods

The disclosure provides various embodiments of catheters that can be used for various procedures. Embodiments of methods are also provided that can be performed with catheters in accordance with the present disclosure.

Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

In situ forming hemostatic foam implants

In situ forming hemostatic form implants

The disclosure provides various embodiments of systems to facilitate the cutting of luminal tissue structures percutaneously.

Tissue cutting systems and methods

Delivery systems for in situ forming foam formulations are provided. The devices may include various actuation mechanisms and may entrain air into fluid formulation components in a variety of ways, including mixing with air and the addition of compressed gas.

Delivery system for in situ forming foams and methods of using the same

Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An illustrative annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. An improved protective device can be placed between the annuloplasty device and an underlying coronary artery to inhibit compression of the underlying coronary artery by the annuloplasty device in the coronary sinus. In addition, the protective device can inhibit compression of the coronary artery from inside the heart, such as from a prosthetic mitral valve that exerts radially outward pressure toward the coronary artery. The annuloplasty device can also create an artificial inner ridge or retaining feature projecting into the native mitral valve region to help secure a prosthetic mitral valve.

Annuloplasty procedures, related devices and methods

Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms are disclosed. The systems include an insertable medical device and an in-situ forming foam that is formed from a polymer that reacts in an aqueous environment. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.

In-situ forming foams for treatment of aneurysms

The present disclosure provides a variety of prostheses, delivery systems and techniques to facilitate closure of transvascular or transcameral access ports. Various embodiments of prostheses are provided including a plurality of radially expandable mesh discs filled with material to facilitate coagulation and to reduce or stop leakage from punctures in vessel walls.

Devices and methods for closure of transvascular or transcameral access ports

Systems and method for treating aneurysms are provided which utilize formulations that form polymer foams in situ. The formulations generally have a buoyancy greater than or less than blood, and either float to the top of the aneurysm and foam from the top down or sink to the bottom and foam from the bottom up.

Systems and methods for the treatment of aneurysms

Growing community of inventors

Medford, MA, United States of America

Rany Busold