Immunitybio, Inc.

Ranjeet Sinha

Rohit Duggal

Patrick Soon-Shiong

Jason Isaacson

Karl Marquez

Wenzhao Li

Cord blood or peripheral blood NK cells are prepared from whole blood mononuclear cells without the need to isolate CD34+ hematopoietic stem cells or NK cells, and without the need for a feeder layer. Advantageously, the methods presented herein use an enrichment process that uses antiCD16 agonist antibodies, antiCD3 antibodies, and N-803. Moreover, contemplated processes are suitable for adaptation into a fully automated production process (GMP in a box).

Mononuclear cell derived NK cells

Provided herein are methods and customized media compositions for culturing CIK NKT cells.

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San Diego, CA, United States of America

Ranjeet Sinha