Aurobindo Pharma Limited

Rani Ananta

Sivakumaran Meenakshisunderam

Sukumar Nandi

Sambhu Prasad Sarma Mallela

Ramesh Dandala

Gangadhara Bhima Shankar Nangi

Islam Aminul

Naresh Akkina

Venkata Vara Prasada Rao Korrapati

Venkata Subramanyeswara Rao Inti

Balanarasimha Reddy Gona

The present invention provides an improved process for the preparation of Dutasteride (I) which comprises: (i) reacting 4-aza-5&#x3b1;-androst-1-en-3-one-17&#x3b2;-carboxylic acid (VII), Formula VII with sulfonic acid anhydride (RSO)O in presence of base to produce an intermediate compound of Formula (XIII), wherein R represents Calkyl, Chalo alkyl, Caryl, halo aryl; (ii) condensing compound of Formula (XIII) with 2,5-bis(trifluoromethyl)aniline (III), Formula (III) in the presence or absence of a base to produce Dutasteride (I). 

Process for the preparation of Dutasteride

The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of formula (I), which is an useful intermediate in the preparation of Rosuvastatin. 

Process for preparing pyrimidine propenaldehyde

The present invention relates to an improved process for the preparation of 2-n-butyl-3-[[2'-(1H-tetrazol-5-yl)[1,1&#x2032;-biphenyl]-4-yl]-1,3-diazaspiro[4.4]non--en-4-one (Irbesartan).

Process for the preparation of Irbesartan

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Hyderabad Telangana, India

Rani Ananta