Free Radical Sciences

Randy D White

Gary Pace

Deborah Rice

Joseph A Safron

Daniel M Wilson

Donovan E Gordon

Dennis I Goldberg

A method is provided for reducing side effects caused by chemotherapeutic agents by administering to a patient in need thereof a therapeutically effective amount of a composition including L-2-oxothiazolidine-4-carboxylate specifically for reducing hemorrhagic cystitis in a patient at risk of same.

Method of reducing cyclophosphamide induced hemorrhagic cystitis

The present invention provides a method for reducing, or preventing, bone marrow hypoplasia in a patient at risk of, or having, same. To this end, when a glutathione intracellular stimulator is administered to such a patient, the risk of bone marrow hypoplasia is reduced or prevented. In an embodiment, the composition for stimulating the intracellular glutathione levels comprises L-2-oxothiazolidine-4-carboxylate.

Method of reducing or preventing bone marrow hypoplasia

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Crystal Lake, IL, United States of America

Randy D White