Emory University

Randolph E Patterson

Mark M Goodman

R Wayne Alexander

David Chappell

Compounds of the invention have the general structure ##STR1## X, Y or Z are, respectively independently, H, F or an isotope thereof, Br or an isotope thereof, I or an isotope thereof, At or an isotope thereof, (R.sub.1)W or (R.sub.2)V and R is --(R.sub.1)W, when W is H or F or an isotope thereof, R.sub.1 is linear or branched alkyl of 1-4 carbon atoms, R.sub.2 is vinyl, V is I or an isotope thereof and at least one of X, Y or Z is not H. The compounds of the invention bind to PK receptors.

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Atlanta, GA, United States of America

Randolph E Patterson